Evaluating Headspace Component Vapor鈥揟ime Profiles by Solid-Phase Microextraction with External Sampling of an Internal Standard

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• 作者：William MacCrehan ; Stephanie Moore ; Michele Schantz
• 刊名：Analytical Chemistry
• 出版年：2011
• 出版时间：November 15, 2011
• 年：2011
• 卷：83
• 期：22
• 页码：8560-8565
• 全文大小：757K
• 年卷期：v.83,no.22(November 15, 2011)
• ISSN：1520-6882

文摘

The vapor鈥搕ime profiles of explosive materials are of valuable interest to Homeland Security, providing critical information that can aid in the detection of explosive-containing devices. An approach is described that achieves reproducible characterization of volatile components as a function of time based on comparison of the sample response to an externally sampled internal standard (ESIS). Utilizing nonequilibrium solid-phase microextraction (SPME) measurements, this SPME-ESIS technique improves reproducibility (reported as percent relative standard deviation) of vapor鈥搕ime profiles by approximately an order of magnitude and allows for an equitable comparison of the target compound between diverse materials. Two odorants associated with canine detection of explosives, 2-ethyl-1-hexanol and 2,4-dinitrotoluene, are used to optimize parameters for the SPME-ESIS technique.