Trifluoromethylallylation of Heterocyclic C–H Bonds with Allylic Carbonates under Rhodium Catalysis

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• 作者：Miji Choi ; Jihye Park ; Satyasheel Sharma ; Hyeim Jo ; Sangil Han ; Mijin Jeon ; Neeraj Kumar Mishra ; Sang Hoon Han ; Jong Suk Lee ; In Su Kim
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：June 3, 2016
• 年：2016
• 卷：81
• 期：11
• 页码：4771-4778
• 全文大小：468K
• 年卷期：0
• ISSN：1520-6904

文摘

The rhodium(III)-catalyzed γ-trifluoromethylallylation of various heterocyclic C–H bonds with CF₃-substituted allylic carbonates is described. These reactions provide direct access to linear CF₃-containing allyl frameworks with complete trans-selectivity via C–H bond activation followed by a formal S_N-type reaction pathway.