7,7-Dimethylaporphine and Other Alkaloids from the Bark of Guatteria friesiana
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- 作者：Emmanoel V. Costa ; Maria Lúcia B. Pinheiro ; Beatriz Helena L. N. S. Maia ; Francisco A. Marques ; Ana Lúcia T. G. Ruiz ; Gabriela M. Marchetti ; João Ernesto de Carvalho ; Milena B. P. Soares ; Cinara O. S. Costa ; Alexandre F. C. Galvão ; Norberto P. Lopes ; Hector H. F. Koolen ; Daniel P. Bezerra ; Andersson Barison
- 刊名：Journal of Natural Products
- 出版年：2016
- 出版时间：June 24, 2016
- 年：2016
- 卷：79
- 期：6
- 页码：1524-1531
- 全文大小：312K
- 年卷期：0
- ISSN：1520-6025
文摘
Phytochemical investigation of the bark of Guatteria friesiana afforded 12 new aporphines (1–12), along with nine known alkaloids (13–21). The structures of the new alkaloids were determined on the basis of spectroscopic data interpretation. The cytotoxic activity of the isolated compounds against a small panel of tumor cell lines was assessed using the Alamar blue assay.