Scalable and Selective Preparation of 3,3′,5,5′-Tetramethyl-2,2′-biphenol

详细信息    查看全文

• 作者：Thomas Quell ; Nadine Hecken ; Katrin M. Dyballa ; Robert Franke ; Siegfried R. Waldvogel
• 刊名：Organic Process Research & Development
• 出版年：2017
• 出版时间：January 20, 2017
• 年：2017
• 卷：21
• 期：1
• 页码：79-84
• 全文大小：355K
• ISSN：1520-586X

文摘

Biphenols are indispensable building blocks in ligand systems for organic catalysis. 3,3′5,5′-Tetramethyl-2,2′-biphenol is a particular versatile motif in different catalytic systems. We developed an easy to perform and scalable process to give access to large quantities of this important building block by the use of selenium dioxide, a common and readily available oxidizer.