Detection of Explosives as Negative Ions Directly from Surfaces Using a Miniature Mass Spectrometer

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• 作者：Nathaniel L. Sanders ; Sameer Kothari ; Guangming Huang ; Gary Salazar ; R. Graham Cooks
• 刊名：Analytical Chemistry
• 出版年：2010
• 出版时间：June 15, 2010
• 年：2010
• 卷：82
• 期：12
• 页码：5313-5316
• 全文大小：166K
• 年卷期：v.82,no.12(June 15, 2010)
• ISSN：1520-6882

文摘

A miniature mass spectrometer was modified by incorporating a conversion dynode detector system and the appropriate electronics to allow the detection of negatively charged ions. The system was fitted with a discontinuous atmospheric pressure interface to allow external ionization by desorption electrospray ionization (DESI). It was used to identify the explosives 2,4,6-trinitrotoluene (TNT), 2,4,6-trinitrophenyl-N-methylnitramine (Tetryl), and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocane (HMX) present in trace amounts on surfaces (500 pg/cm² to 1 μg/cm²) both individually and as components of mixtures. Detection of explosives was demonstrated in the presence of an interfering matrix. A large surface (5 cm ×15 cm) on which 1 μg/cm² samples of TNT, Tetryl, and HMX had been spotted randomly was interrogated in 22 s in the full scan mode, and signals characteristic of each of the explosives were observed in the DESI mass spectrum.