Temporal Changes of PBDE Levels in California House Cats and a Link to Cat Hyperthyroidism

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• 作者：Weihong Guo ; Stephen Gardner ; Simon Yen ; Myrto Petreas ; June-Soo Park
• 刊名：Environmental Science & Technology
• 出版年：2016
• 出版时间：February 2, 2016
• 年：2016
• 卷：50
• 期：3
• 页码：1510-1518
• 全文大小：338K
• ISSN：1520-5851

文摘

In this study, we measured serum PBDE levels in California (CA) house cats during two time periods: 2008–2010 and 2012–2013 to assess the impacts of the decline in use of these materials after the bans. The median ∑₁₉PBDE level in CA household cats (age ≥10 yr) was 3479 ng/g lipid in 2008–2010 (1st time period, n = 21) and 1518 ng/g lipid in 2012–2013 (2nd time period, n = 22), about 2 times lower than in the first time period (p = 0.006). In contrast, PCB and OCP levels showed no statistically significant changes. With better matched group size and age (HT = 11 vs non-HT = 11, age ≥10 yr) in the second time period, we found that ∑₁₉PBDE level (mean ± SE ng/g lipid) was significantly higher in the HT group (3906 ± 1442) than those in the non-HT group (1125 ± 244) (p = 0.0030). Higher levels of PCBs and OCPs were also found in HT group. Despite the declines of PBDE levels, our findings indicate that the current levels of PBDEs, as well as PCBs and OCPs, may still pose health effects for house cats and, possibly, humans.