The liquid–liquid–solid equilibria of the two quaternary systems sodium chloride + rubidium chloride + (1-propanol or 2-propanol) + water were investigated at 25 °C. The binodal curves and tie lines together with the integrated phase diagrams for the two quaternary systems have been determined to investigate salting effects. The different equilibrium regions are discussed in detail. The results of the fitting for experimental tie line data by the Eisen−Joffe equation are reasonable.