Copper-Mediated Reaction of Zirconacyclopentadienes with Azides: A One-Pot Three-Component Synthesis of Multiply Substituted Pyrroles from One Azide and Two Alkynes
A general method for the synthesis of multiply substituted pyrroles through zirconocene-mediated coupling of two alkynes and an azide in the presence of CuCl has been achieved.