Palladium-Catalyzed Regio- and Stereoselective Hydrosilylation of Electron-Deficient Alkynes

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• 作者：Yuto Sumida ; Tomoe Kato ; Suguru Yoshida ; Takamitsu Hosoya
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：March 16, 2012
• 年：2012
• 卷：14
• 期：6
• 页码：1552-1555
• 全文大小：297K
• 年卷期：v.14,no.6(March 16, 2012)
• ISSN：1523-7052

文摘

Highly regio- and stereoselective hydrosilylation applicable to a broad range of electron-deficient alkynes has been established using palladium catalysis. The synthetic utility of the method has been demonstrated by further transformations of 伪-silylalkenes, particularly Hiyama coupling and stereoinverting iododesilylation followed by Suzuki鈥揗iyaura coupling, which enables stereodivergent syntheses of 伪-arylenoates.