Cu(OAc)2-Mediated Cascade Annulation of Diarylalkyne Sulfonamides through Dual C–N Bond Formation: Synthesis of 5,10-Dihydroindolo[3,2-b]indoles
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- 作者：Junchao Yu ; Daisy Zhang-Negrerie ; Yunfei Du
- 刊名：Organic Letters
- 出版年：2016
- 出版时间：July 15, 2016
- 年：2016
- 卷：18
- 期：14
- 页码：3322-3325
- 全文大小：386K
- 年卷期：0
- ISSN：1523-7052
文摘
An unusual cascade reaction featuring annulation of diarylalkyne sulfonamides to form 5,10-dihydroindolo[3,2-b]indoles has been realized with Cu(OAc)2 as the sole oxidant. This unprecedented process encompasses two sequential C–N bond formations, allowing for an efficient synthesis of the biologically important indoloindole derivatives.