Coordination-Induced Assembly of Coordination Polymer Submicrospheres: Promising Antibacterial and in Vitro Anticancer Activities

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• 作者：Kuaibing Wang ; Xiaoyan Ma ; Dalin Shao ; Zhirong Geng ; Zhiyang Zhang ; Zhilin Wang
• 刊名：Crystal Growth & Design
• 出版年：2012
• 出版时间：July 3, 2012
• 年：2012
• 卷：12
• 期：7
• 页码：3786-3791
• 全文大小：467K
• 年卷期：v.12,no.7(July 3, 2012)
• ISSN：1528-7505

文摘

Spheres-like coordination polymer architectures in submicro regimes have been synthesized from the hydrothermal reaction of transition metal ions and 3,5-bis(pyridin-3-ylmethylamino)benzoic acid (L1). The size of the final coordination polymer was dependent on the concentrations of reactants. Scanning electron microscopy studies monitored at numerous stages of growth reveal that coordination-induced morphology changes from uncoordinated flowerlike ligands to sphere-like coordination polymer particles. Moreover, variations of luminescent and antibacterial profiles are associated with coordination environments or the size of as-obtained coordination polymer samples. In addition, the newly synthesized Cu-based polymer particles may act as novel metal-based anticancer drugs in the future because of their potent in vitro anticancer activities against three chosen cancer lines MCF-7, HeLa, and NCI-H446.