Copper-Catalyzed Regioselective 1,2-Alkylesterification of Dienes to Allylic Esters

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• 作者：Yougui Li ; Yulong Han ; Haigen Xiong ; Nengbo Zhu ; Bo Qian ; Changqing Ye ; Eric Assen B. Kantchev ; Hongli Bao
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：February 5, 2016
• 年：2016
• 卷：18
• 期：3
• 页码：392-395
• 全文大小：370K
• ISSN：1523-7052

文摘

Copper catalyzed 1,2-alkylesterification of 1,3-dienes with diacyl peroxides affords branched allylic esters in excellent regioselectivity, including products with a newly generated fully substituted carbon center. The only byproduct is CO₂. The reaction proceeds by a radical mechanism as suggested by spin trap and crossover experiments.