Insulin-like growth factor 1 (IGF-1) regulates prolactin, growth hormone, and IGF-1 receptor expression in the pituitary gland of the gilthead sea bream Sparus aurata

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• 作者：Khaled Mohammed-Geba ; J. A. Martos-Sitcha…
• 关键词：GH ; In vitro ; IGF ; 1 ; IGF ; 1Ra ; Pituitary ; PRL
• 刊名：Fish Physiology and Biochemistry
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：42
• 期：1
• 页码：365-377
• 全文大小：1,036 KB
• 参考文献：Arias A (1976) Sobre la biología de la dorada, Sparus aurata, L., de los esteros de la provincia de Cádiz. Investigación Pesquera 40:201–222
  Canosa LF, Chang JP, Peter RE (2007) Neuroendocrine control of growth hormone in fish. Gen Comp Endocrinol 151:1–26CrossRef PubMed
  Dai X, Zhang W, Zhuo Z, He J, Yin Z (2015) Neuroendocrine regulation of somatic growth in fishes. Sci China Life Sci 58(2):137–147CrossRef PubMed
  Dantzer B, Swanson EM (2012) Mediation of vertebrate life histories via insulin-like growth factor-1. Biol Rev Camb Philos Soc 87:414–429CrossRef PubMed
  Elies G, Groigno L, Wolff J, Boeuf G, Boujard D (1996) Characterization of the insulin-like growth factor type 1 receptor messenger in two teleost species. Mol Cell Endocrinol 124:131–140CrossRef PubMed
  Eppler E, Jevdjovic T, Maake C, Reinecke M (2007) Insulin-like growth factor I (IGF-1) and its receptor (IGF-1R) in the rat anterior pituitary. Eur J Neurosci 25:191–200CrossRef PubMed
  Escobar S, Fuentes EN, Poblete E, Valdés JA, Safian D, Reyes AE, Álvarez M, Molina A (2011) Molecular cloning of IGF-1 and IGF-1 receptor and their expression pattern in the Chilean flounder (Paralichthys adspersus). Comp Biochem Physiol 159:140–147CrossRef
  Fruchtman S, Gift B, Howes B, Borski R (2001) Insulin-like growth factor-I augments prolactin and inhibits growth hormone release through distinct as well as overlapping cellular signaling pathways. Comp Biochem Physiol 129:237–242CrossRef
  Fruchtman S, McVey DC, Borski RJ (2002) Characterization of pituitary IGF-1 receptors: modulation of prolactin and growth hormone. Am J Physiol 283:R468–R476
  Fuentes J, Brinca L, Guerreiro PM, Power DM (2010) PRL and GH synthesis and release from the sea bream (Sparus auratus L.) pituitary gland in vitro in response to osmotic challenge. Gen Comp Endocrinol 168:95–102CrossRef PubMed
  Fuentes EN, Björnsson BT, Valdés JA, Einarsdottir IE, Lorca B, Alvarez M, Molina A (2011) IGF-1/PI3 K/Akt and IGF-1/MAPK/ERK pathways in vivo in skeletal muscle are regulated by nutrition and contribute to somatic growth in the fine flounder. Am J Physiol 300:R1532–R1542
  Gabillard JC, Weil C, Rescan PY, Navarro I, Gutiérrez J, Le Bail PY (2003) Effects of environmental temperature on IGF1, IGF2, and IGF type I receptor expression in rainbow trout (Oncorhynchus mykiss). Gen Comp Endocrinol 133:233–242CrossRef PubMed
  Gallardo MA, Castejon C, Navarro I, Blasco J, Gutiérrez J, Sánchez J (2001) L-leucine and l -alanine uptake by trout (Salmo trutta) cardiomyocytes: the effect of IGF-I and insulin. Fish Physiol Biochem 25:239–248CrossRef
  Gómez-Requeni P, Mingarro M, Calduch-Giner JA, Médale F, Martin SAM, Houlihan DF, Kaushik S, Pérez-Sánchez J (2004) Protein growth performance, amino acid utilisation and somatotropic axis responsiveness to fish meal replacement by plant protein sources in gilthead sea bream (Sparus aurata). Aquaculture 232:493–510CrossRef
  Greene MW, Chen TT (1999) Characterization of teleost insulin receptor family members. II. Developmental expression of insulin-like growth factor type I receptor messenger RNAs in rainbow trout. Gen Comp Endocrinol 115:270–281CrossRef PubMed
  Gutiérrez J, Párrizas M, Maestro MA, Navarro I, Plisetskaya EM (1995) Insulin and IGF-I binding and tyrosine kinase activity in fish heart. J Endocrinol 146(1):35–44CrossRef PubMed
  Kajimura S, Uchida K, Yada T, Hirano T, Aida K, Gordon Grau E (2002) Effects of insulin-like growth factors (IGF-1 and -II) on growth hormone and prolactin release and gene expression in euryhaline tilapia, Oreochromis mossambicus. Gen Comp Endocrinol 127:223–231CrossRef PubMed
  Laiz-Carrión R, Guerreiro PM, Fuentes J, Canario AV, Martín Del Río MP, Mancera JM (2005a) Branchial osmoregulatory response to salinity in the gilthead sea bream, Sparus auratus. J Exp Zool 303A:563–576CrossRef
  Laiz-Carrión R, Sangiao-Alvarellos S, Guzmán JM, Martín del Río MP, Soengas JL, Mancera JM (2005b) Growth performance of gilthead sea bream Sparus aurata in different osmotic conditions: implications for osmoregulation and energy metabolism. Aquaculture 250:849–861CrossRef
  Laiz-Carrión R, Fuentes J, Redruello B, Guzmán JM, Martín del Río MP, Power D, Mancera JM (2009) Expression of pituitary prolactin, growth hormone and somatolactin is modified in response to different stressors (salinity, crowding and food-deprivation) in gilthead sea bream Sparus auratus. Gen Comp Endocrinol 162:293–300CrossRef PubMed
  Lammers R, Gray A, Schlessinger J, Ullrich A (1989) Differential signaling potential of insulin- and IGF-1-receptor cytoplasmic domains. EMBO J 8:1369–1375PubMedCentral PubMed
  Le Roith D, Bondy C, Yakar S, Liu JL, Butler A (2001) The somatomedin hypothesis: 2001. Endocr Rev 22:53–74CrossRef PubMed
  Leatherland JF, Li M, Barkataki S (2010) Stressors, glucocorticoids and ovarian function in teleosts. J Fish Biol 76(1):86–111CrossRef PubMed
  Li Q, You C, Liu L, Rao Z, Sima X, Zhou L, Xu J (2013) Craniopharyngioma cell growth is promoted by growth hormone (GH) and is inhibited by tamoxifen: involvement of growth hormone receptor (GHR) and IGF-1 receptor (IGF-1R). J Clin Neurosci 20:153–157CrossRef PubMed
  Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real time quantitative PCR and the 2-ΔΔCT method. Methods 25:402–408CrossRef PubMed
  Makino K, Onuma TA, Kitahashi T, Ando H, Ban M, Urano A (2007) Expression of hormone genes and osmoregulation in homing chum salmon: a minireview. Gen Comp Endocrinol 152:304–309CrossRef PubMed
  Mancera JM, McCormick SD (1998) Osmoregulatory actions of the GH/IGF axis in non-salmonid teleosts. Comp Biochem Physiol 121(1):43–48CrossRef
  Mancera JM, McCormick SD (2007) Role of prolactin, growth hormone, insulin-like growth factor I and cortisol in teleost osmoregulation. In: Kapoor BG, Baldisserotto B, Mancera Romero JM (eds) Fish osmoregulation. Science Publishers, Enfield, pp 497–515CrossRef
  Mancera JM, Fernández-Llebrez P, Pérez-Fígares JM (1993) Osmoregulatory responses during abrupt salinity changes in the euryhaline gilthead sea bream (Sparus aurata L.). Comp Biochem Physiol 106:245–250CrossRef
  Mancera JM, Laiz-Carrión R, Martín del Río MP (2002) Osmoregulatory action of PRL, GH, and cortisol in the gilthead seabream (Sparus aurata L.). Gen Comp Endocrinol 129:95–103CrossRef
  Marchler-Bauer A, Lu S, Anderson JB, Chitsaz F, Derbyshire MK, DeWeese-Scott C, Fong JH, Geer LY, Geer RC, Gonzales NR, Gwadz M, Hurwitz DI, Jackson JD, Ke Z, Lanczycki CJ, Lu F, Marchler GH, Mullokandov M, Omelchenko MV, Robertson CL, Song JS, Thanki N, Yamashita RA, Zhang D, Zhang N, Zheng C, Bryant SH (2011) CDD: a Conserved Domain Database for the functional annotation of proteins. Nucleic Acids Res 39:D225–D229PubMedCentral CrossRef PubMed
  Martos-Sitcha JA, Wunderink YS, Gozdowska M, Kulczykowska E, Mancera JM, Martínez-Rodríguez G (2013) Vasotocinergic and isotocinergic systems in the gilthead sea bream (Sparus aurata): an osmoregulatory story. Comp Biochem Physiol 166:571–581CrossRef
  Martos-Sitcha JA, Fuentes J, Mancera JM, Martínez-Rodríguez G (2014) Variations in the expression of vasotocin and isotocin receptor genes in the gilthead sea bream Sparus aurata during different osmotic challenges. Gen Comp Endocrinol 197:5–17CrossRef PubMed
  Maures T, Chan SJ, Xu B, Sun H, Ding J, Duan C (2002) Structural, biochemical, and expression analysis of two distinct insulin-like growth factor I receptors and their ligands in zebrafish. Endocrinol 143:1858–1871
  McCormick SD (2001) Endocrine control of osmoregulation in teleost fish. Am Zool 41:781–794
  Mei J, Yan W, Fang J, Yuan G, Chen N, He Y (2014) Identification of a gonad-expression differential gene insulin-like growth factor-1 receptor (Igf1r) in the swamp eel (Monopterus albus). Fish Physiol Biochem 40:1181–1190PubMed
  Mohammed-Geba K, Mancera JM, Martínez-Rodríguez G (2015) Acclimation to different environmental salinities induces molecular endocrine changes in the GH/IGF-1 axis of juvenile gilthead sea bream (Sparus aurata L.). J Comp Physiol B 185(1):87–101CrossRef PubMed
  Nakao N, Tanaka M, Higashimoto Y, Nakashima K (2002) Molecular cloning, identification and characterization of four distinct receptor subtypes for insulin and IGF-I in Japanese flounder, Paralichthys olivaceus. J Endocrinol 173:365–375CrossRef PubMed
  Ness JK, Wood TL (2002) Insulin-like growth factor I, but not neurotrophin-3, sustains Akt activation and provides long-term protection of immature oligodendrocytes from glutamate-mediated apoptosis. Mol Cell Neurosci 20:476–488CrossRef PubMed
  NetNGlyc (1985) Software: N-glycosylation sites. NetNGlyc 1.0 Server: http://​www.​cbs.​dtu.​dk/​services/​NetNGlyc/​
  Otteson DC, Cirenza PF, Hitchcock PF (2002) Persistent neurogenesis in the teleost retina: evidence for regulation by the growth-hormone/insulin-like growth factor-I axis. Mech Dev 117:137–149CrossRef PubMed
  Pérez-Sánchez J, Marti-Palanca H, Le Bail P-Y (1994) Seasonal changes in circulating growth hormone (GH), hepatic GH-binding and plasma insulin-like growth factor-I immunoreactivity in a marine fish, gilthead sea bream, Sparus aurata. Fish Physiol Biochem 13:199–208CrossRef PubMed
  Persson P, Sundell K, Björnsson BT, Lundqvist H (1998) Calcium metabolism and osmoregulation during sexual maturation of river running Atlantic salmon. J Fish Biol 52:334–349CrossRef
  Petersen TN, Brunak S, von Heijne G, Nielsen H (2011) SignalP 4.0: discriminating signal peptides from transmembrane regions. Nat Methods 8:785–786CrossRef PubMed
  Reindl KM, Sheridan MA (2012) Peripheral regulation of the growth hormone-insulin-like growth factor system in fish and other vertebrates. Comp Biochem Physiol 163:231–245CrossRef
  Reinecke M, Björnsson BT, Dickhoff WW, McCormick SD, Navarro I, Power DM, Gutiérrez J (2005) Growth hormone and insulin-like growth factors in fish: where we are and where to go. Gen Comp Endocrinol 142:20–24CrossRef PubMed
  Romanelli RJ, LeBeau AP, Fulmer CG, Lazzarino DA, Hochberg A, Wood TL (2007) Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt. J Biol Chem 282(31):22513–22524CrossRef PubMed
  Sakamoto T, McCormick SD (2006) Prolactin and growth hormone in fish osmoregulation. Gen Comp Endocrinol 147(1):24–30CrossRef PubMed
  Sánchez-Gurmaches J, Cruz-Garcia L, Ibarz A, Fernández-Borrás J, Blasco J, Gutiérrez J, Navarro I (2013) Insulin, IGF-1, and muscle MAPK pathway responses after sustained exercise and their contribution to growth and lipid metabolism regulation in gilthead sea bream. Domest Anim Endocrinol 45:145–153CrossRef PubMed
  Seale AP, Yamaguchi Y, Johnstone WM 3rd, Borski RJ, Lerner DT, Gordon Grau E (2013) Endocrine regulation of prolactin cell function and modulation of osmoreception in the Mozambique tilapia. Gen Comp Endocrinol 192:191–203CrossRef PubMed
  Shamblott MJ, Cheng CM, Bolt D, Chen TT (1995) Appearance of insulin-like growth factor mRNA in the liver and pyloric ceca of a teleost in response to exogenous growth hormone. Proc Natl Acad Sci USA 92(15):6943–6946PubMedCentral CrossRef PubMed
  Tamura K, Stecher G, Peterson D, Filipski A, Kumar S (2013) MEGA6: molecular evolutionary genetics analysis version 6.0. Mol Biol Evol 30(12):2725–2729PubMedCentral CrossRef PubMed
  Tipsmark CK, Luckenbach JA, Madsen SS, Kiilerich P, Borski RJ (2008) Osmoregulation and expression of ion transport proteins and putative claudins in the gill of Southern flounder (Paralichthys lethostigma). Comp Biochem Physiol 150A:265–273CrossRef
  Ullrich A, Gray A, Tam AW, Yang-Feng T, Tsubokawa M, Collins C, Henzel W, Le Bon T, Kathuria S, Chen E (1986) Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J 5(10):2503–2512PubMedCentral PubMed
  Upton Z, Yandell CA, Degger BG, Chan SJ, Moriyama S, Francis GL, Ballard FJ (1998) Evolution of insulin-like growth factor-I (IGF-1) action: in vitro characterization of vertebrate IGF-1 proteins. Comp Biochem Physiol 121:35–41CrossRef
  Vargas-Chacoff L, Astola A, Arjona FJ, Martín del Río MP, García-Cózar F, Mancera JM, Martínez-Rodríguez G (2009a) Gene and protein expression for prolactin, growth hormone and somatolactin in Sparus aurata: seasonal variations. Comp Biochem Physiol 153:130–135CrossRef
  Vargas-Chacoff L, Astola A, Arjona FJ, Martín del Río MP, García-Cózar F, Mancera JM, Martínez-Rodríguez G (2009b) Pituitary gene and protein expression under experimental variation on salinity and temperature in gilthead sea bream Sparus aurata. Comp Biochem Physiol 154B:303–308CrossRef
  Xu Y, Zang K, Liu X, Shi B, Li C, Shi X (2015) Insulin-like growth factors I and II in starry flounder (Platichthys stellatus): molecular cloning and differential expression during embryonic development. Fish Physiol Biochem 41:139–152CrossRef PubMed
  
• 作者单位：Khaled Mohammed-Geba (1) (2) (3)
  J. A. Martos-Sitcha (1) (2)
  A. Galal-Khallaf (1) (2) (3)
  J. M. Mancera (2)
  G. Martínez-Rodríguez (1)
  
  1. Departamento de Biología Marina y Acuicultura, Instituto de Ciencias Marinas de Andalucía, Consejo Superior de Investigaciones Científicas (ICMAN-CSIC), 11510, Puerto Real, Cádiz, Spain
  2. Departamento de Biología, Facultad de Ciencias del Mar y Ambientales, Universidad de Cádiz, Campus de Excelencia Internacional del Mar (CEIMAR), 11510, Puerto Real, Cádiz, Spain
  3. Genetic Engineering and Molecular Biology Division, Department of Zoology, Faculty of Sciences, Menoufia University, Shebin El-Kom, Menoufia, Egypt
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Hydrobiology
  Animal Physiology
  Animal Anatomy, Morphology and Histology
  Animal Biochemistry
  Zoology
  
• 出版者：Springer Netherlands
• ISSN：1573-5168

文摘

The role of insulin-like growth factor 1 (IGF-1) on regulation of growth hormone (GH) and prolactin (PRL) as well as the possible involvement of IGF-1 receptor subtype a (IGF-1Ra) mRNA was assessed in juvenile specimens of Sparus aurata. IGF-1Ra was successfully cloned, and active receptor domains were localized in its mRNA precursor. Also, phylogenetic analysis of the protein sequence indicated a closer proximity to IGF-1Ra isoform found in zebrafish and other teleosts, than to the isoform IGF-1Rb. The most abundant presence of IGF-1Ra mRNA was detected in white muscle, whereas head kidney showed the lowest gene expression among 24 different studied tissues. Pituitaries of juvenile specimens of S. aurata were incubated in vitro with different doses of IGF-1 (0, 1, 100, and 1000 ng mL−1) during a period of 10 h. Total RNA with a high quality could be obtained from these pituitaries. PRL mRNA expression significantly increased with increasing IGF-1 doses. Similarly, IGF-1Ra mRNA increased its expression in response to IGF-1. However, GH mRNA levels decreased in a dose-dependent manner after IGF-1 treatment. The contradictory responses of GH and PRL expressions to IGF-1 in our experiment are possibly mediated by IGF-1Ra presence on the somatotrophs and prolactotrophs. The increase in IGF-1Ra mRNA levels may be related to the proper activation of the PI3-K/Akt signal transduction pathways which are normally involved in GH and PRL regulation. Keywords GH In vitro IGF-1 IGF-1Ra Pituitary PRL