刊名:Graefe's Archive for Clinical and Experimental Ophthalmology
出版年:2016
出版时间:January 2016
年:2016
卷:254
期:1
页码:59-67
全文大小:891 KB
参考文献:1.Age-Related Eye Disease Study Research Group (2001) The Age-related Eye disease study system for classifying age-related macular degeneration from stereoscopic color fundus photographs: the age-related Eye disease study report number 6. Am J Ophthalmol 132:668–681CrossRef 2.Klein R, Davis MD, Magli YL, Segal P, Klein BE, Hubbard L (1991) The Wisconsin age-related maculopathy grading system. Ophthalmology 98:1128–1134PubMed CrossRef 3.Spaide RF, Curcio C (2010) Drusen characterization with multimodal imaging. Retina 30:1441–1454PubMed PubMedCentral CrossRef 4.Holz FG, Strauss EC, Schmitz-Valckenberg S, van Lookeren CM (2014) Geographic atrophy: clinical features and potential therapeutic approaches. Ophthalmology 121:1079–1091PubMed CrossRef 5.Klein ML, Ferris FL 3rd, Armstrong J, Hwang TS, Chew EY, Bressler SB et al (2008) Retinal precursors and the development of geographic atrophy in age-related macular degeneration. Ophthalmology 115:1026–1031PubMed CrossRef 6.Sarks JP, Sarks SH, Killingsworth MC (1988) Evolution of geographic atrophy of the retinal pigment epithelium. Eye 2(Pt 5):552–577PubMed CrossRef 7.Gass JD (1973) Drusen and disciform macular detachment and degeneration. Arch Ophthalmol 90:206–217PubMed CrossRef 8.Ferris FL, Davis MD, Clemons TE, Lee LY, Chew EY, Lindblad AS et al (2005) A simplified severity scale for age-related macular degeneration: AREDS report No. 18. Arch Ophthalmol 123:1570–1574PubMed CrossRef 9.Ferris FL 3rd, Wilkinson CP, Bird A, Chakravarthy U, Chew E, Csaky K et al (2013) Clinical classification of age-related macular degeneration. Ophthalmology 120:844–851PubMed CrossRef 10.Yehoshua Z, Wang F, Rosenfeld PJ, Penha FM, Feuer WJ, Gregori G (2011) Natural history of drusen morphology in age-related macular degeneration using spectral domain optical coherence tomography. Ophthalmology 118:2434–2441PubMed PubMedCentral CrossRef 11.Delori FC, Fleckner MR, Goger DG, Weiter JJ, Dorey CK (2000) Autofluorescence distribution associated with drusen in age-related macular degeneration. Invest Ophthalmol Vis Sci 41:496–504PubMed 12.Lois N, Owens SL, Coco R, Hopkins J, Fitzke FW, Bird AC (2002) Fundus autofluorescence in patients with age-related macular degeneration and high risk of visual loss. Am J Ophthalmol 133:341–349PubMed CrossRef 13.Sunness JS, Ziegler MD, Applegate CA (2006) Issues in quantifying atrophic macular disease using retinal autofluorescence. Retina 26:666–672PubMed CrossRef 14.Khanifar AA, Koreishi AF, Izatt JA, Toth CA (2008) Drusen ultrastructure imaging with spectral domain optical coherence tomography in age-related macular degeneration. Ophthalmology 115:1883–1890PubMed PubMedCentral CrossRef 15.Leuschen JN, Schuman SG, Winter KP, McCall MN, Wong WT, Chew EY et al (2013) Spectral-domain optical coherence tomography characteristics of intermediate age-related macular degeneration. Ophthalmology 120:140–150PubMed PubMedCentral CrossRef 16.Schuman SG, Koreishi AF, Farsiu S, Jung SH, Izatt JA, Toth CA (2009) Photoreceptor layer thinning over drusen in eyes with age-related macular degeneration imaged in vivo with spectral-domain optical coherence tomography. Ophthalmology 116:488–496, e2PubMed PubMedCentral CrossRef 17.Sadigh S, Cideciyan AV, Sumaroka A, Huang WC, Luo X, Swider M et al (2013) Abnormal thickening as well as thinning of the photoreceptor layer in intermediate age-related macular degeneration. Invest Ophthalmol Vis Sci 54:1603–1612PubMed CrossRef 18.Ouyang Y, Heussen FM, Hariri A, Keane PA, Sadda SR (2013) Optical coherence tomography-based observation of the natural history of drusenoid lesion in eyes with dry age-related macular degeneration. Ophthalmology 120:2656–2665PubMed CrossRef 19.Landa G, Rosen RB, Pilavas J, Garcia PM (2012) Drusen characteristics revealed by spectral-domain optical coherence tomography and their corresponding fundus autofluorescence appearance in dry age-related macular degeneration. Ophthalmic Res 47:81–86PubMed CrossRef 20.Delori FC, Dorey CK, Staurenghi G, Arend O, Goger DG, Weiter JJ (1995) In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics. Invest Ophthalmol Vis Sci 36:718–729PubMed 21.Von Rückmann A, Fitzke FW, Bird AC (1995) Distribution of fundus autofluorescence with a scanning laser ophthalmoscope. Br J Ophthalmol 79:407–412CrossRef 22.Schmitz-Valckenberg S, Jorzik J, Unnebrink K, Holz FG (2002) Analysis of digital scanning laser ophthalmoscopy fundus autofluorescence images of geographic atrophy in advanced age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 240:73–78PubMed CrossRef 23.Schmitz-Valckenberg S, Brinkmann CK, Alten F, Herrmann P, Stratmann NK, Göbel AP et al (2011) Semiautomated image processing method for identification and quantification of geographic atrophy in age-related macular degeneration. Invest Ophthalmol Vis Sci 52:7640–7646PubMed CrossRef 24.Helb HM, Charbel Issa P, Fleckenstein M, Schmitz-Valckenberg S, Scholl HP, Meyer CH et al (2010) Clinical evaluation of simultaneous confocal scanning laser ophthalmoscopy imaging combined with high-resolution, spectral-domain optical coherence tomography. Acta Ophthalmol 88:842–849PubMed CrossRef 25.Fleckenstein M, Charbel Issa P, Helb HM, Schmitz-Valckenberg S, Finger RP, Scholl HP et al (2008) High-resolution spectral domain-OCT imaging in geographic atrophy associated with age-related macular degeneration. Invest Ophthalmol Vis Sci 49:4137–4144PubMed CrossRef 26.Pircher M, Gotzinger E, Findl O, Michels S, Geitzenauer W, Leydolt C et al (2006) Human macula investigated in vivo with polarization-sensitive optical coherence tomography. Invest Ophthalmol Vis Sci 47:5487–5494PubMed CrossRef 27.Querques G, Georges A, Ben Moussa N, Sterkers M, Souied EH (2014) Appearance of regressing drusen on optical coherence tomography in age-related macular degeneration. Ophthalmology 121:173–179PubMed CrossRef 28.Farsiu S, Chiu SJ, O’Connell RV, Folgar FA, Yuan E, Izatt JA et al (2014) Quantitative classification of eyes with and without intermediate age-related macular degeneration using optical coherence tomography. Ophthalmology 121:162–172PubMed PubMedCentral CrossRef 29.Yehoshua Z, Gregori G, Sadda SR, Penha FM, Goldhardt R, Nittala MG et al (2013) Comparison of drusen area detected by spectral domain optical coherence tomography and color fundus imaging. Invest Ophthalmol Vis Sci 54:2429–2434PubMed PubMedCentral CrossRef 30.Bellmann C, Holz FG, Schapp O, Völcker HE, Otto TP (1997) Topography of fundus autofluorescence with a new confocal scanning laser ophthalmoscope. Ophthalmologe 94:385–391PubMed CrossRef 31.Bindewald A, Bird AC, Dandekar SS, Dolar-Szczasny J, Dreyhaupt J, Fitzke FW et al (2005) Classification of fundus autofluorescence patterns in early age-related macular disease. Invest Ophthalmol Vis Sci 46:3309–3314PubMed CrossRef 32.Einbock W, Moessner A, Schnurrbusch UE, Holz FG, Wolf S (2005) Changes in fundus autofluorescence in patients with age-related maculopathy. Correlation to visual function: a prospective study. Graefes Arch Clin Exp Ophthalmol 243:300–305PubMed CrossRef 33.Spaide RF (2003) Fundus autofluorescence and age-related macular degeneration. Ophthalmology 110:392–399PubMed CrossRef 34.Toy BC, Krishnadev N, Indaram M, Cunningham D, Cukras CA, Chew EY et al (2013) Drusen regression is associated with local changes in fundus autofluorescence in intermediate age-related macular degeneration. Am J Ophthalmol 156:532–542, e1PubMed PubMedCentral CrossRef
作者单位:Arno P. Göbel (1) Monika Fleckenstein (1) Tjebo F. C. Heeren (1) Frank G. Holz (1) Steffen Schmitz-Valckenberg (1)
1. Department of Ophthalmology, University of Bonn, Ernst-Abbe-Str. 2, 53127, Bonn, Germany
刊物类别:Medicine
刊物主题:Medicine & Public Health Ophthalmology
出版者:Springer Berlin / Heidelberg
ISSN:1435-702X
文摘
Purpose To determine fundus autofluorescence (FAF) signal variations and corresponding microstructural alterations on spectral-domain optical coherence tomography (SD-OCT) in areas of funduscopically visible drusen associated with age-related macular degeneration (AMD).