A comparative biomechanical study of a novel integrated plate spacer for stabilization of cervical spine: An in vitro human cadaveric model

详细信息	查看全文 | 推荐本文 |

• 作者：Kamran Majid^a ; ^{kmajid@orthospinesp.com} ; Suresh Chinthakunta^b ; ^{schinthakunta@globusmedical.com} ; Aditya Muzumdar^b ; ^{amuzumdar@globusmedical.com} ; Saif Khalil^b ; ^{skhalil@globusmedical.com}
• 关键词：Integrated plate spacer ; Anterior cervical plate ; Cervical spine ; Biomechanical study ; Spacer
• 刊名：Clinical Biomechanics
• 出版年：2012
• 期刊代码：56_02680033
• 类别：med
• 出版时间：July, 2012
• 卷：27
• 期：6
• 页码：532-536
• 文件大小：454 K

摘要

Background

Integrated plate-spacer may provide adequate construct stability while potentially lowering operative time, decreasing complications, and providing less mechanical obstruction. The purpose of the current study was to compare the biomechanical stability of an anatomically profiled 2-screw integrated plate-spacer to a traditional spacer only and to a spacer and anterior cervical plate construct. In addition, the biomechanical stability of 2-screw integrated plate-spacer was compared to a commercially available 4-screw integrated plate-spacer.

Methods

Two groups, each of nine cervical cadaver spines (C2-C7), were tested under pure moments of 1.5 Nm. Range of motion was recorded at C5-C6 in all loading conditions (flexion, extension, lateral bending, and axial rotation) for the following constructs: 1) Intact; 2) 2-screw or 4-screw integrated plate-spacer; 3) spacer and anterior cervical plate; and 4) spacer only.

Findings

All fusion constructs significantly reduced motion compared to the intact condition. Within the instrumented constructs, spacer and anterior cervical plate, 2-screw and 4-screw integrated plate-spacer resulted in reduced motion compared to the spacer only construct. No significant differences were found in motion between any of the instrumented conditions in any of the loading conditions.

Interpretation

The application of integrated plate-spacer for anterior cervical discectomy and fusion is based on several factors including surgical ease-of-use, biomechanical characteristics, and surgeon preference. The study suggests that integrated plate-spacer provide biomechanical stability comparable to traditional spacer and plate constructs in the cervical spine. Clinical studies on integrated plate spacer devices are necessary to understand the performance of these devices in vivo.