• 作者：J.M. Ló ; pez Á ; lvarez^a ; ^{jmloal@hotmail.com} ; M.E. Valeró ; n Lemaur^a ; O. Pé ; rez Quevedo^a ; J.M. Limiñ ; ana Cañ ; al^b ; A. Jimé ; nez Bravo de Laguna^a ; E. Consuegra Llapurt^a ; A. Moró ; n Saé ; n de Casas^a ; R. Gonzá ; lez Jorge^a
• 关键词：Traumatismo craneoencefá ; lico pediá ; trico ; Factores pronó ; sticos ; Morbilidad ; Mortalidad
• 刊名：Medicina Intensiva
• 出版年：2011
• 期刊代码：pca255_02105691
• 类别：med
• 出版时间：August-September 2011
• 卷：35
• 期：6
• 页码：337-343
• 文件大小：224 K

Objective

To describe the factors associated to morbidity-mortality in pediatric patients with severe head injury (SHI).

Material and method

A review was made of the patients admitted to the Pediatric Intensive Care Unit (PICU) with SHI between July 1983 and December 2009.

Results

Of the 389 patients with head injuries, 174 (45%) presented SHI. The mean age of these subjects was 67 (9) months, with a Glasgow Coma Score (GCS) of 5.5 (1.8) and a PRISM score of 10.6 (6.7). Thirty-nine percent of the patients showed diffuse encephalic injury (DEI) in the computed tomography (CT) study. Seventy-nine percent of the patients subjected to intracranial pressure monitoring (ICP) presented intracranial hypertension. These patients had a greater incidence of serious sequelae (66.7 vs. 23.1%; p = 0.01). Sequelae of clinical relevance were recorded in 59 patients (34%), and proved serious in 64%of the cases. The mortality rate among the patients with SHI was 24.7%, and mortality was significantly associated with a lower GCS score, hyperglycemia, intracranial hypertension and the presence of mydriasis or shock. The mortality rate associated to severe DEI was significantly higher than in the case of mild-moderate DEI (87.5 vs. 7.2%; p < 0.001).

The independent mortality risk factors in the pediatric patients with SHI were found to be the presence of mydriasis (OR: 31.27), intracranial hypertension (OR: 13.23) and hyperglycemia (OR: 3.10).

Conclusions

a) SHI in pediatric patients was associated with high morbidity-mortality; b) intracranial hypertension was associated to the development of serious sequelae; c) independent mortality risk factors were the existence of mydriasis, intracranial hypertension and hyperglycemia.