Apparatus and methods for treatment of HIV infections and AIDS
- 作者：Naficy ; Sadeque S
- 刊名：Transfusion Science
- 出版年：1996
- 期刊代码：250_09553886
- 类别：med
- 出版时间：March, 1996
- 卷：17
- 期：1
- 页码：II
- 文件大小：74.3 K
摘要
An extracorporeal apparatus and methods for treatment of HIV (Human Immuno-deficiency Virus) infections and AIDS. Infected blood is drawn from a patient and separated into infected components (comprising plasma, cell-free virus, and infected white cells containing replicating virus) and uninfected components (comprising red cells and platelets). The uninfected components are returned to the patient and the infected components are treated with organic agents. The preferred organic agent is diethyl ether which is used in an amount and over a period of time sufficient to kill the infected cells and the cell-free virus. The preferred apparatus functions at temperatures below 56 degrees C., and includes centrifugal separators for separating the infected components from healthy components; mixers and agitators inside an air-tight chamber void of oxygen where the infected components are mixed and treated with ether; centrifuges and distillators working under vacuum which remove the ether after the completion of treatment; a gas chromatograph with automatic sampling for determining the residues of ether and the safety of the treated components; and mechanisms for returning the treated and safe components, in conjunction with intravenous fluids, separately or together with the healthy components, to the patient. The treatment cycle is repeated until the patient's blood is made free of virus.