Detection of type-specific antibodies to HSV-1 and HSV-2: comparative analysis of a chemiluminescence immunoassay with a conventional ELISA

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• 作者：Amelia W. Maters^a ; Christina V. Wright^a ; Maria Teresa Lee^a ; Greta Schwichtenberg^b ; Barbara Detrick^a ; ^{bdetrick@jhmi.edu}
• 关键词：HSV-1 ; HSV-2 ; Serology ; Chemiluminescence ; ELISA
• 刊名：Diagnostic Microbiology and Infectious Disease
• 出版年：2012
• 期刊代码：79_07328893
• 类别：med
• 出版时间：July, 2012
• 卷：73
• 期：3
• 页码：273-274
• 文件大小：128 K

摘要

Type-specific serologic tests for human herpes simplex virus (HSV) are critically important for sexually transmitted disease evaluation. We compared the LIAISON庐 HSV-1 and HSV-2 Type Specific assays relative to an established commercial ELISA. The overall agreement of the chemiluminescence immunoassay versus the ELISA assay was 99.6%(HSV-1) and 100%(HSV-2). The LIAISON庐 methodology has several advantages.