Future thinking in Parkinson's disease: An executive function?

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• 作者：Stefania de Vito^a ; ^b ; ^{stefaniadv29@libero.it} ; Nadia Gamboz^b ; Maria Antonella Brandimonte^b ; Paolo Barone^c ; ^d ; Marianna Amboni^c ; ^d ; Sergio Della Sala^a
• 关键词：Future thinking ; Executive functions
• 刊名：Neuropsychologia
• 出版年：2012
• 期刊代码：205_00283932
• 类别：med
• 出版时间：June, 2012
• 卷：50
• 期：7
• 页码：1494-1501
• 文件大小：433 K

摘要

Contrary to what was originally thought () recent data have shown that imagining the future is not entirely dependent on the hippocampus () and neuroimaging studies have demonstrated a frontopolar activation during future thinking tasks (). The present study investigated whether the performance of people with Parkinson's disease (PD) on future simulation tasks was dependent on memory or executive control. Thirty-one PD patients, asked to imagine possible future scenarios, generated fewer future episodic details than matched controls. The seven patients who clearly performed below the range of controls in future thinking, were also significantly poorer on the Frontal Assessment Battery (FAB), a battery assessing executive control, but showed no deficits in immediate or delayed memory tests. These results suggest that poor performance in the future thinking task is associated with poor executive control and less so with memory impairment. Flexible searching activities of past details might be crucial capacities for envisaging one's own future.