Synthesis of magnetic 伪-Fe₂O₃ and Fe₃O₄ hollow nanospheres for sustained release of ibuprofen

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• 作者：Manickam Sasidharan^a ; Hom Nath Luitel^a ; Nanda Gunawardhana^a ; Masamichi Inoue^b ; Shin-ichi Yusa^b ; Takanori Watari^a ; Kenichi Nakashima^a ; ^{nakashik@cc.saga-u.ac.jp}
• 关键词：伪-Fe2O3 ; Fe3O4 ; Hollow nanospheres ; Micelles ; Soft-template
• 刊名：Materials Letters
• 出版年：2012
• 期刊代码：59_0167577x
• 类别：ms
• 出版时间：15 April, 2012
• 卷：73
• 期：Complete
• 页码：4-7
• 文件大小：507 K

摘要

A soft template method is reported for fabrication of porous 伪-Fe₂O₃ and Fe₃O₄ hollow nanospheres of size 32 卤 2 nm. A new triblock copolymer micelle poly(styrene-b-acrylic acid-b-ethylene oxide) with core-shell-corona architecture has been used as soft template. The hollow nanospheres were thoroughly characterized by transmission electron microscope, superconducting quantum interference device (SQUID), X-ray diffraction, nitrogen adsorption/desorption analyses, dynamic light scattering, infrared spectroscopy, and thermal analysis. The efficiency of magnetic hollow nanospheres as drug-delivery carriers was investigated using ibuprofen as a model drug.