Updated Brazilian STR allele frequency data using over 100,000 individuals: An analysis of CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, Penta D, Penta E, TH01, TPOX and vWA loci

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• 作者：Vitor Rezende da Costa Aguiar^a ; ¹ ; Eldamá ; ria de Vargas Wolfgramm^a ; ¹ ; Frederico Scott Varella Malta^b ; ² ; Adriana Gonç ; alves Bosque^b ; ² ; Amanda de Castro Mafia^b ; ² ; Vanessa Cristina de Oliveira Almeida^b ; ² ; Fabiola de Andrade Caxito^b ; ² ; Victor Cavalcanti Pardini^b ; ² ; Alessandro Clayton Souza Ferreira^b ; Iú ; ri Drumond Louro^a ; ^{iurilouro@yahoo.com}
• 关键词：Autosomal STRs ; Allelic frequencies ; Population data ; Brazil
• 刊名：Forensic Science International ; Genetics
• 出版年：2012
• 期刊代码：18_18724973
• 类别：bio
• 出版时间：July, 2012
• 卷：6
• 期：4
• 页码：504-509
• 文件大小：253 K

摘要

The Brazilian population is one of the most heterogeneous populations of the world, formed mainly by an admixture of European, African and Native American populations. Brazil is the fifth largest country in the world (8,511,960 km²), being divided into five geographical regions. This study provides population genetic data of up to 137,161 unrelated individuals representing the entire Brazilian territory. Allelic frequencies and other population data analysis are reported for the 15 autosomal STR loci included in the PowerPlex^庐16 kit (Promega Corporation, Madison, WI, USA). In order to guarantee that individuals were not related, we have considered only F1 data from couples undergoing paternity testing. The number of individuals genotyped for each locus was: CSF1PO (113,526); D3S1358 (135,133); D5S818 (135,181); D7S820 (137,136); D8S1179 (134,211); D13S317 (137,161); D16S539 (136,942); D18S51 (136,739); D21S11 (130,014); FGA (135,839); Penta D (110,333); Penta E (128,055); TH01 (112,695); TPOX (123,102); vWA (127,415). Allele sizes ranged from 1 to 48.2. Statistic parameters (PD, PIC and Ho; considering values 鈮?.75) suggest that markers D13S317, D16S539, D18S51, D21S11, D7S820, D8S1179, Penta D, Penta E, TH01, FGA and vWA were more informative for genetic identification purposes in the Brazilian population.