Improving hemocompatibility of styrene-b-(ethylene-co-butylene)-b-styrene elastomer via N-vinyl pyrrolidone-assisted grafting of poly(ethylene glycol) methacrylate

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• 作者：Huawei Yang^a ; ^c ; Shifang Luan^a ; ^{sfluan@ciac.jl.cn} ; Jie Zhao^a ; Hengchong Shi^a ; Xiaomeng Li^a ; ^c ; Lingjie Song^a ; ^c ; Jing Jin^a ; ^c ; Qiang Shi^a ; Jinghua Yin^a ; ^{yinjh@ciac.jl.cn} ; Dean Shi^b ; Paola Stagnaro^d
• 关键词：Styrenic thermoplastic elastomer ; Melt free radical grafting ; Poly(ethylene glycol)
• 刊名：Polymer
• 出版年：2012
• 期刊代码：83_00323861
• 类别：ms
• 出版时间：3 April, 2012
• 卷：53
• 期：8
• 页码：1675-1683
• 文件大小：1271 K

摘要

In this work, in order to enhance the grafting degree, N-vinyl pyrrolidone (NVP) was used to assist the melt grafting of the macromonomer-poly(ethylene glycol) methyl ether methacrylate (PEGM)-which has good hemocompatible property, onto styrene-b-(ethylene-co-butylene)-b-styrene (SEBS) elastomer with free radical initiator. The grafting degree of PEGM with NVP assistance was increased by at least 4-fold to those without NVP. In addition, side reactions such as homopolyerization of the PEGM monomer during the melt grafting process could be largely reduced in the NVP-assisted system. Both the hydrophilicity and hemocompatibility of the PEGM modified SEBS were highly improved. Comparing to virgin SEBS, the amount of fibrinogen adsorption was reduced by up to 75%in the NVP-assisted grafting samples.