LR-CAHSQC: an application of a Carr–Purcell–Meiboom–Gill-type sequence to heteronuclear multiple bond correlation spectroscopy

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• 作者：Koskela ; Harri ; Kilpelä ; inen ; Ilkka ; Heikkinen ; Sami
• 关键词：2D NMR ; Heteronuclear long-range coupling constants ; CPMG ; HSQC
• 刊名：Journal of Magnetic Resonance
• 出版年：2003
• 期刊代码：126_10907807
• 类别：ch
• 出版时间：October, 2003
• 卷：164
• 期：2
• 页码：228-232
• 文件大小：195 K

摘要

A new pulse sequence, long-range CPMG-adjusted heteronuclear single quantum coherence (LR-CAHSQC), is proposed for the determination of long-range J_CH coupling constants from a long-range ¹H–¹³C correlation experiment. The long-range heteronuclear coupling constants can be directly extracted from COSY-type antiphase peak patterns. The current approach utilizes CPMG-sequences for polarization transfer, and thus avoids the evolution of homonuclear J_HH couplings, which normally may introduce abnormalities into the cross peak pattern. The differences between LR-CAHSQC and normal LR-HSQC are discussed.