Changes in the seroepidemiology of hepatitis B infection in Catalonia 1989–1996

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• 作者：Dom&iacute ; nguez ; Angela ; Bruguera ; Miquel ; Vidal ; Josep ; Plans ; Pere ; Salleras ; Llu&iacute ; s
• 关键词：Seroepidemiological survey ; Hepatitis B ; Vaccination programmes
• 刊名：Vaccine
• 出版年：2000
• 期刊代码：89_0264410x
• 类别：imm
• 出版时间：May, 2000
• 卷：18
• 期：22
• 页码：2345-2350
• 文件大小：110 K

摘要

The objective of this study was to investigate the prevalence of hepatitis B markers in a representative sample of 2142 subjects in Catalonia, Spain, and to compare it with previous studies. Multiple logistical regression analysis was carried out to determine variables associated with the markers studied. The prevalence of anti-HBc and HBsAg was 9.1%and 1.2%, respectively. Male gender, urban habitat, birth place outside Catalonia and lower social class were associated with the presence of anti-HBc. Carrier status was only associated with male gender. Between 1989 and 1996 there was a decrease of 46%in the prevalence of serum HBV markers mainly in the 25–44 (P<0.0001) and 35–64 year (P