• 作者：E. de Carlos Iriarte^a ; ^{escair@yahoo.es} ; A. Cabezó ; n Hedo^b ; M. Mosquera Gonzá ; lez^c ; G. Rodrí ; guez Caravaca^c ; J.M. Ruiz-Soldevilla^d ; B. Sancho Pé ; rez^e
• 关键词：Dolor en c&aacute ; ncer de mama ; Toxina botul&iacute ; nica ; Mastectom&iacute ; a ; Reconstrucci&oacute ; n con implantes ; Calidad de vida
• 刊名：Rehabilitaci贸n
• 出版年：2012
• 期刊代码：pca300_00487120
• 类别：med
• 出版时间：April-June, 2012
• 卷：46
• 期：2
• 页码：112-119
• 文件大小：543 K

class="h4">Introduction

Pain is common among patients with breast cancer, it being the leading cause of poor quality of life. Botulinum toxin (BT)may be a treatment option in these patients during breast reconstruction or in post-mastectomy pain syndrome. Very few authors have studied its effectiveness in treating pain.

class="h4">Hypothesis

Infiltration with BTin the breast muscle causes an inhibition of the muscle spasm, thus improving the pain.

class="h4">Objectives

To assess the effectiveness of BT in pain control in reconstruction with tissue expanders, breast implants and in chronic pain.

class="h4">Material and methods

The study had a quasi-experimental design. The sample included 89 randomly selected patients between June 2009 and February 2011. All had breast cancer with controlled disease and painful contracture of the pectoralis major. The evaluation was performed by clinical examination and score on the visual analogue scale (VAS) before and after the infiltration.

class="h4">Results

A total of 21%had undergone infiltration during reconstruction; 16%had a breast prosthesis and 63%had chronic pain. Nociceptive pain was more frequent in the expander (73.6%) and mixed chronic pain (89.2%) group. Initial VAS score was higher for the expander group that obtained greater declines after the injection.

class="h4">Conclusions

Infiltration of the pectoral muscle with BT type A improves pain in breast cancer subjects, both during breast reconstruction with expander and in patients with implants and in those with post-mastectomy pain syndrome.