Participation rates in the selection of population controls in a case-control study of colorectal cancer using two recruitment methods

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• 作者：Gemma Castañ ; o-Vinyals^a ; ^b ; ^c ; ^{gcastano@creal.cat} ; Mark J. Nieuwenhuijsen^a ; ^b ; ^c ; Ví ; ctor Moreno^d ; ^e ; Estela Carrasco^a ; ^b ; Elisabet Guinó ; ^d ; Manolis Kogevinas^a ; ^b ; ^c ; ^f ; Cristina M. Villanueva^a ; ^b ; ^c
• 关键词：Patient participation rates ; Population controls ; Case-control study
• 刊名：Gaceta Sanitaria
• 出版年：2011
• 期刊代码：pca166_02139111
• 类别：med
• 出版时间：September-October 2011
• 卷：25
• 期：5
• 页码：353-356
• 文件大小：71 K

摘要

Objectives

Low participation rates in the selection of population controls are an increasing concern for the validity of case-control studies worldwide.

Methods

We conducted a pilot study to assess two approaches to recruiting population controls in a study of colorectal cancer, including a face-to-face interview and blood sample collection. In the first approach, persons identified through a population roster were invited to participate through a telephone call by an interviewer telephoning on behalf of our research center. In the second approach, individuals were identified from the lists of selected family practitioners and were telephoned on behalf of the family practitioner.

Results

When the second method was used, participation rates increased from 42%to 57%and the percentage of refusals decreased from 47%to 13%. The reasons for refusing to participate did not differ significantly between the two methods.

Conclusions

Contact through the family practitioner yielded higher response rates in population controls in the study area.