Extra cytoplasmic function 蟽 factor activation

详细信息	查看全文 | 推荐本文 |

• 作者：Theresa D Ho ; Craig D Ellermeier ^{craig-ellermeier@uiowa.edu}
• 刊名：Current Opinion in Microbiology
• 出版年：2012
• 期刊代码：25_13695274
• 类别：imm
• 出版时间：April, 2012
• 卷：15
• 期：2
• 页码：182-188
• 文件大小：373 K

摘要

The bacterial cell envelope is essential for cell viability and is a target for numerous antibiotics and host immune defenses. Thus bacteria must sense and respond to damage to the cell envelope. Many bacteria utilize alternative 蟽 factors such as extracytoplasmic function (ECF) 蟽 factors to respond to cell envelope stress. Although ECF 蟽 factors are utilized by both Gram negative and Gram positive bacteria to respond to cell envelope stress, the mechanisms of sensing differ. In this review, we examine the events and proteins that are required for activation of two model extracytoplasmic function 蟽 factors, 蟽^E in E. coli and 蟽^W in B. subtilis.