Ductus venosus Doppler velocimetry in normal pregnancies from 11 to 13聽+聽6 weeks' gestation鈥擜 Taiwanese study

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• 作者：Chien-Chih Tseng^a ; Hsing-I Wang^b ; ^c ; Peng-Hui Wang^a ; ^d ; Ming-Jie Yang^a ; ^d ; Chi-Mou Juang^a ; ^d ; Huann-Cheng Horng^a ; ^d ; Yi-Cheng Wu^a ; Chia-Chien Chen^a ; Huei-Ling Shiu^a ; Mei-Mei Chiang^a ; Huei-Jie Lin^a ; Chih-Yao Chen^a ; ^b ; ^d ; ^{zachary.joyce@gmail.com} ; Kuan-Chong Chao^a ; ^d
• 关键词：D-wave ; diastolic wave velocity ; ductus venosus ; fetal color Doppler ultrasound ; NT ; nuchal translucency ; PIV ; pulsatility index for veins ; RI ; resistance index ; S-wave ; systolic wave velocity
• 刊名：Journal of the Chinese Medical Association
• 出版年：2012
• 期刊代码：210_17264901
• 类别：med
• 出版时间：April, 2012
• 卷：75
• 期：4
• 页码：171-175
• 文件大小：475 K

摘要

Background

To investigate flow in the ductus venosus at 11-13聽+聽6 weeks of gestation in women with normal pregnancies in the Taiwanese population.

Methods

Two hundred and fifty-two normal singleton pregnancies with gestational ages ranging from 11 to 13聽+聽6 weeks were examined in this study. The pulsatility index for veins (PIV), resistance index (RI), peak velocity during ventricular systole (S-wave), and peak velocity during ventricular diastole (D-wave) were recorded from the ductus venosus.

Results

We analyzed 252 participants who all fulfilled the inclusion and exclusion criteria of our study. The mean maternal age was 31 (range 19-45 years), with a corresponding gestational age of 12聽+聽4 weeks (range 11-13聽+聽6). No significant change was found in the vascular indices as gestational age increased for the S-wave (S-wave = 1.4214 (GA) + 17.448, r = 0.09, P聽=聽0.154), PIV (PIV = 鈭?.0358 (GA) + 1.4143, r = 鈭?.05, P = 0.378) and RI (RI = 鈭?.035 (GA)聽+聽1.1478, r = 鈭?.064, P聽=聽0.468). In contrast, the D-wave behaved differently from the other variables. There was a significant increase (r聽=聽0.155, P聽=聽0.013) in the D-wave with gestational age (D-wave聽=聽1.4896 (GA) - 7.1547).

Conclusion

D-wave velocity in the ductus venosus increased with gestational age. S-wave peak velocity showed an increasing trend and PIV showed a decreasing trend with gestational age, but they did not reach statistical significance.