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Predicci贸n del grado de minusval铆a en pacientes con esclerosis m煤ltiple
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摘要

Introduction and objectives

Multiple sclerosis (MS) is most frequent and disabling chronic neurological disease in young adults. This study has aimed to, based on the relation between EDSS (Expanded Disability Status Scale of Kurtzke) and the grade of handicap of MS patients, obtain a predictor of the handicap grade that would allow the clinicians to orient the patient on the social aid program and tax benefits that they are entitled to.

Material and methods

A cross-sectional study was performed on 67 MS-diagnosed patients who had been previously assigned a EDSS grade of disability during their respective neurological evaluations. After, we evaluated the individual handicap grade in these patients, using the scale for the 鈥淭he Grade of handicap鈥?(RD 1971/1999, of 23 december). The statistical study of the data was performed using the last generation statistical program of R Development Core Team (R).

Results

P.Mi = handicap degree (EDSS value dependent)

伪 = -14.23

尾 = 12.49

ei = biological variability

Using this model, we calculated the percentages of handicap for each value of the EDSS with a 95%confidence interval.

Conclusions

The statistical model allows us to use the Kurtzke Expanded Disability Status Scale as a predictor of the handicap grade of MS patients.

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