• 作者：Juan L. Bonilla-Palomas<sup> ; sup><sup>jnlsbnll@hotmail.comsup> ; Antonio L. Gá ; mez-Ló ; pez ; Manuel P. Anguita-Sá ; nchez ; Juan C. Castillo-Domí ; nguez ; Daniel Garcí ; a-Fuertes ; Manuel Crespin-Crespin ; Amador Ló ; pez-Granados ; José ; Suá ; rez de Lezo
• 关键词：AC ; aclaramiento de creatinina ; EN ; estado nutricional ; IAM ; infarto agudo de miocardio ; IC ; insuficiencia cardiaca ; IMC ; í ; ndice de masa corporal ; MNA ; Mini Nutritional Assessment
• 刊名：Revista Espa帽ola de Cardiolog铆a
• 出版年：2011
• 期刊代码：pca308_03008932
• 类别：med
• 出版时间：September 2011
• 卷：64
• 期：9
• 页码：752-758
• 文件大小：236 K

ss="h4">Introduction and objectives

The prevalence of malnutrition among patients with heart failure and the role it might play in prognosis is not currently known. The aim of this study was to analyse the prevalence and risk of malnutrition as well as its possible influence on long-term mortality in patients with heart failure.

ss="h4">Methods

A prospective analysis was conducted on 208 patients discharged consecutively from our centre between January 2007 and March 2008 after being hospitalised with heart failure. Before discharge, a complete nutritional assessment was performed and diagnosis of malnutrition and risk of malnutrition was done with the Mini Nutritional Assessment. Its possible independent association with mortality was assessed by a Cox multivariate analysis.

ss="h4">Results

The mean age of the patients was 73 卤 10 years, with 46%women; the most common aetiology of heart failure was ischaemia (41%). In addition, 13%were classified as malnourished, 59.5%at risk of malnutrition and 27.5%were well-nourished. At a median follow-up of 25 months, mortality in the three groups was 76%, 35.9%and 18.9%, respectively (log-rank, P < .001). In the Cox multivariate analysis, the malnutrition state was an independent predictor of mortality (hazard ratio 3.75, 95%confidence interval, 1.75-8.02, P = .001).

ss="h4">Conclusions

Malnutrition and the risk of malnutrition are highly prevalent in patients hospitalised for heart failure. Furthermore, we found that the state of malnutrition as defined by the Mini Nutritional Assessment survey is an independent predictor of mortality in these patients.

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