• 作者：Sara Manrique Arija^a ; ^{sarama_82@hotmail.com} ; Marí ; a Ló ; pez Lasanta^a ; Francisco G. Jimé ; nez Nú ; ñ ; ez^a ; Inmaculada Ureñ ; a^a ; Pilar Espiñ ; o-Lorenzo^b ; Carmen M. Romero Barco^a ; Marí ; a Á ; ngeles Ló ; pez Belmonte^a ; Virginia Coret^a ; Marí ; a Victoria Irigoyen^a ; Antonio Ferná ; ndez Nebro^a ; ^c
• 关键词：Artroplastia ; Artritis reumatoide ; Cadera ; Evoluci&oacute ; n ; Pr&oacute ; tesis ; Tendencia ; Rodilla
• 刊名：Reumatolog铆a Cl铆nica
• 出版年：2011
• 期刊代码：pca303_1699258X
• 类别：med
• 出版时间：November-December 2011
• 卷：7
• 期：6
• 页码：380-384
• 文件大小：201 K

Objective

To determine the annual number and trend of prostheses implanted in patients with rheumatoid arthritis (RA) at our hospital during the past decade.

Materials and methods

Retrospective observational study. Patients were collected through an extensive search of the database of the Clinical Documentation Service between 1998 and 2007. The data was extracted from medical records using a predesigned questionnaire. Statistical analysis of longitudinal prostheses was made by Cochrane's Q test and the Kaplan-Meier method.

Results

Sixty-one RA patients were operated on with 78 prostheses as a direct result of their disease at our hospital between 1998 and 2007. Most were women (80%) with positive rheumatoid factor (84%). The mean age was 58 years, and the average time since onset of RA was 13 years. All but one had previously received antirheumatic drugs (88%methotrexate), but only 11%had biological therapy. No changes were observed in the number of arthroplasties as a whole over a decade, although there was a trend towards reduction in the number of patients that required a knee replacement for the first time (Cochrane Q, P = 0.05).

Conclusion

We observed no significant changes in trends in the number of new joint replacement procedures as a whole in the past decade at our hospital, although the number of patients that required knee replacement for the first time as a direct result of their underlying disease seems to have declined in the last decade.