To validate the technique to measure placental vascularization grade through three-dimensional power Doppler during the second trimester of pregnancy.
Seventy-five pregnant women with no antecedents or obstetric diseases were studied through ultrasound with threedimensional power Doppler and application of the VOCAL system. Validation of the 芦placental vascular biopsy禄 for the evaluation of placental vascularization was performed by comparing three methods to obtain vascular parameters: with only one biopsy, with three biopsies of the same central volume of the placenta, and with three biopsies of different volumes. To evaluate the intraobserver correlation, we analyzed the intraclass correlation index (ICC).
A good correlation was found between the age of the pregnant woman, parity and week of delivery with the vascularization indexes. The ICC for the vascularization indexes were acceptable when three biopsies were analyzed.
Reliable vascularization parameters can be determined by obtaining only one volume from the most central part of the placenta and subsequently analyzing three biopsies of this volume.