Non-resective surgery and radiosurgery for treatment of drug-resistant epilepsy

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• 作者：Pantaleo Romanelli^a ; ^{radiosurgery2000@yahoo.com} ; Pasquale Striano^b ; Manlio Barbarisi^c ; Giangennaro Coppola^d ; David J. Anschel^e
• 关键词：Deep brain stimulation ; Epilepsy ; Vagal nerve stimulation ; Multiple subpial transections ; Neuromodulation ; Stereotactic radiosurgery
• 刊名：Epilepsy Research
• 出版年：2012
• 期刊代码：87_09201211
• 类别：med
• 出版时间：May, 2012
• 卷：99
• 期：3
• 页码：193-201
• 文件大小：358 K

摘要

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Summary

Epilepsy surgery is an effective treatment for properly selected patients with intractable seizures. However, many patients with medically intractable epilepsy are not excellent candidates for surgical resection of the epileptogenic zone. Due to recent advances in computer technology and bioengineering, several novel techniques are receiving increasing interest for their role in the care of people with epilepsy. Neuromodulation is an emerging surgical option to be used when conventional resective surgery is not indicated. We review the indications and expected outcomes of neuromodulatory treatments currently available for the treatment of refractory epilepsy, i.e., vagus nerve stimulation, deep brain stimulation, stereotactic radiosurgery, and multiple subpial transections.