Human papillomavirus-related genital disease in the immunocompromised host: Part II

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• 作者：Rachel H. Gormley ; MD^a ; Carrie L. Kovarik ; MD^a ; ^b ; ^{Carrie.Kovarik@uphs.upenn.edu}
• 关键词：AIDS ; anal intraepithelial neoplasia ; Buschke&ndash ; Lowenstein tumor ; condyloma acuminata ; HIV ; human papillomavirus ; imiquimod ; organ transplant ; penile intraepithelial neoplasia ; vulvar intraepithelial neoplasia
• 刊名：Journal of the American Academy of Dermatology
• 出版年：2012
• 期刊代码：200_01909622
• 类别：med
• 出版时间：June, 2012
• 卷：66
• 期：6
• 页码：883.e1-883.e17
• 文件大小：220 K

摘要

Human papillomavirus is responsible for common condyloma acuminata and a number of premalignant and malignant anogenital lesions. The immunocompromised population is at particular risk because of a higher incidence of malignant transformation. Lesions in this population may prove refractory to standard treatment. This is part II of a two-part review that will discuss the treatment of condyloma acuminata and vaginal, vulvar, penile, and anal intraepithelial neoplasias. This article will provide an updated review of available treatments, with a focus on recent advances and the challenges faced in successfully treating human papillomavirus lesions in the immunocompromised host.