Pseudotumor orbitario refractario tratado con rituximab en paciente con lupus eritematoso sist茅mico. A prop贸sito de un caso
- 作者：Carmen Marí ; a Escudero Gonzá ; lez ; carmenescu1@hotmail.com ; Sergio Rodrí ; guez Montero ; Rosalí ; a Martí ; nez Pé ; rez ; Carolina Pastor Mañ ; osa ; Marí ; a Luisa Velloso Feijoo ; José ; Luis Marenco de la Fuente
- 关键词：Exoftalmos ; Lupus eritematoso sisté ; mico ; Pseudotumor orbitario ; Rituximab
- 刊名：Reumatolog铆a Cl铆nica
- 出版年：2010
- 期刊代码：pca303_1699258X
- 类别：med
- 出版时间：July-August 2010
- 卷：6
- 期：4
- 页码：214-216
- 文件大小：202 K
摘要
Ocular manifestations in Systemic Lupus Erythematosus (SLE) are relatively frequent, with a major prevalence of the Keratoconjunctivitis sicca. Nevertheless, the appearance of unilateral exophthalmos secondary to orbital pseudotumor in patients with SLE is extremely rare, and on occasion it can be refractory to conventional pharmacological treatment (glucocorticoids and immunosuppressants). We present the case of a patient with SLE and orbital pseudotumor refractory to treatment with Cyclophosphamide (CF) and an excellent clinical response, with disappearance of the ophthalmological condition after the beginning of therapy with Rituximab (1g脳2), continuing after the infusion of two complete cycles without incidents.