Hepatitis C virus (HCV) chronically infects approximately 2%of the European population. Antiviral therapy with pegInterferon-
(
PegIFN) and ribavirin (Rbv) is the standard of care, leading to HCV eradication in roughly 50%of patients. IFN-based therapy has been associated with high rates (20%) of central nervous system side effects, but only a few case reports exist on extrapyramidal side effects.