• 作者：Antonio Luis Gá ; mez-Ló ; pez ; ^{agalo1980@hotmail.com} ; Juan Luis Bonilla-Palomas ; Manuel Anguita-Sá ; nchez ; Juan Carlos Castillo-Dominguez ; Daniel Garc&#237 ; a-Fuertes ; Manuel Cresp&#237 ; n-Cresp&#237 ; n ; Amador Ló ; pez-Granados ; José ; Mar&#237 ; a Arizó ; n del Prado ; José ; Suá ; rez De Lezo
• 关键词：Insuficiencia cardiaca ; Obesidad ; Í ; ndice de masa corporal ; Supervivencia ; Pronó ; stico
• 刊名：Cardiocore
• 出版年：2011
• 期刊代码：pca84_1889898X
• 类别：med
• 出版时间：July-September 2011
• 卷：46
• 期：3
• 页码：109-114
• 文件大小：397 K

Introduction and objectives

Observational data suggest a protective effect of obesity in heart failure but the relationship with body composition has not yet been studied. The objective of our study is to examine the prognosis influence of body mass index and body composition.

Methods

Baseline body mass index, tricipital skin-fold and brachial muscle circumference were recorded in 208 patients admitted due to heart failure. They were divided into four groups according to BMI: low weight (<20.5), normal weight (20.5 to <25.5), overweight (25.5 to <30), and obese (鈮?0) and in three groups according to tricipital skin fold and brachial muscle circumference (p<5, p 5鈥?4, p鈮?5).

Results

There was a difference in the mortality rate at 1 year (P<0.001) between low-weight patients and the other groups, with no differences between them: 80%for low-weight patients, 32.6%for normal-weight patients, 21.6%for overweight patients, and 17.9%for obese patients. The same was observed between p<5 tricipital skin fold patients and the other groups (64.3%p<5, 19.1%p 5鈥?5 and 25.4%p鈮?5, P=0.002). No differences were observed between brachial muscle circumference groups. After adjusting for different prognosis variables, body mass index and tricipital skin fold remained as independent predictor of reduced mortality at 1 year in multivariate analysis (Hazard ratio=0.93 [0.87鈥?.98]).

Conclusions

In our study, body mass index is an independent risk factor in heart failure due to the group of low weight patients. The poor survival of this group is associated with a decrease in body composition characterised by a decreased body fat mass.