Food restrictions of patients who are undergoing treatment for oral and oropharyngeal cancer

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• 作者：É ; rika de Paula da Cruz^a ; Tatiana Natasha Toporcov^b ; Ligia Drovandi Braga Rotundo^a ; Maria Gabriela Haye Biazevic^a ; Rosana Sarmento Brasileiro^c ; Marcos Brasilino de Carvalho^c ; Luiz Paulo Kowalski^d ; José ; Leopoldo Ferreira Antunes^b ; ^{leopoldo@usp.br}
• 关键词：Mouth neoplasms ; Pharyngeal neoplasms ; Eating disorders ; Quality of life ; Therapeutics/adverse effects ; Nutrition
• 刊名：European Journal of Oncology Nursing
• 出版年：2012
• 期刊代码：119_14623889
• 类别：med
• 出版时间：July, 2012
• 卷：16
• 期：3
• 页码：253-257
• 文件大小：128 K

摘要

Purpose

Oral squamous cell carcinoma and its treatment are associated with facial disfigurement and functional inabilities that may lead to malnutrition or under nourishment. This study assessed the incidence of food restrictions in patients undergoing treatment for oral and oropharyngeal cancer.

Method

We interviewed 120 patients in two hospitals in S茫o Paulo, Brazil, using a structured food frequency questionnaire comprising the most commonly consumed foods in Brazil. This questionnaire was applied twice; the first time to inform dietary patterns prior to the diagnosis of cancer and the second time to assess recent modifications of diet that were associated with the disease and its treatment. Hospital files provided information on clinical status. Multivariate Poisson regression models assessed covariates with prognostic value.

Results

One third of patients suffered major food restrictions (i.e., they reduced substantially the intake of more than 50%of the most commonly consumed food items before the diagnosis); 39%suffered a less severe condition (they could not eat less than 50%of the most commonly consumed food items before the diagnosis, and they needed changes in food preparation). Larger tumour size (adjusted incidence ratio IR聽=聽1.45), posterior location (IR聽=聽1.33), radiotherapy (IR聽=聽1.84), loss of tongue mobility (IR聽=聽1.36) and loss of teeth (IR聽=聽1.25) in the surgery were associated significantly with the study outcome.

Conclusion

This study identified clinical predictors of food restrictions in patients undergoing treatment for oral and oropharyngeal cancer. This knowledge may contribute to improve patient care and management, and to develop interventions aimed at preventing nutritional depletion of these patients.