• 作者：Javier Garcí ; a Seara^a ; ^{Javier.Garcia.Seara@sergas.es} ; Francisco Gude^b ; ^c ; Pilar Cabanas^a ; José ; Luis Martí ; nez Sande^a ; Xesú ; s Ferná ; ndez Ló ; pez^a ; Juliana Elices^a ; Josep Brugada Terradellas^d ; José ; Ramó ; n Gonzá ; lez Juanatey^a ; ^c
• 关键词：CVRS ; calidad de vida relacionada con la salud ; FlA ; flutter auricular ; ICT ; istmo cavotricuspí ; deo ; MCID ; diferencias clí ; nicas mí ; nimamente importantes ; SRM ; media de respuesta estandarizada ; TE ; tamañ ; o de efecto
• 刊名：Revista Espa帽ola de Cardiolog铆a
• 出版年：2011
• 期刊代码：pca308_03008932
• 类别：med
• 出版时间：May 2011
• 卷：64
• 期：5
• 页码：401-408
• 文件大小：187 K

Introduction and objectives

The aim of the study was to assess and measure health-related quality of life (HRQoL) changes in patients with typical atrial flutter following catheter ablation. The outcome was standardized and normalized to the Spanish population adjusted by age and sex.

Methods

Ninety-five consecutive patients who had undergone cavotricuspid isthmus ablation were included. The SF-36 questionnaire was self-administered before the procedure and at 1-year follow-up. We used the effect size and the standardized response mean as measures of responsiveness to quantify the change in HRQoL and the minimum clinically important difference to assess the smallest difference in score that patients perceived as beneficial.

Results

Of the 95 patients initially included, 88 completed the 1-year follow-up. We observed a large improvement (effect size 鈮?.8) on the physical functioning, role-physical , general health, and vitality scales and on the physical component summary. We detected a moderate improvement (effect size 鈮?.5) on the role-emotional, social functioning, and mental health scales and on the mental component summary. On all scales except bodily pain and social activity, the improvement was clinically perceived by patients.

Conclusions

A clinically significant improvement in HRQoL measures was found in patients with typical atrial flutter who underwent cavotricuspid isthmus catheter ablation.

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