Periconceptional folic acid supplementation among women attending antenatal clinic in Anhui, China: Data from a population-based cohort study

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• 作者：Xiu-Ya Xing ; BA ; MA ^{xiuya_2000@sina.com} (Research Student in Maternal ; Child Health Care) ; Fang-Biao Tao ; BA ; MA ; PhD ; ^{fbtao@126.com} (Professor in Public Health) ; Jia-Hu Hao ; BA ; MA ; MD (Professor in Public Health) ; Kun Huang ; BA ; MA (Lecturer in Maternal ; Child Health Care) ; Zhao-Hui Huang ; BA ; MA (Research Student in Maternal ; Child Health Care) ; Xiao-Ming Zhu ; BA ; MA (Research Student in Maternal ; Child Health Care) ; Li-Min Xiao ; BA ; MA (Research Student in Maternal ; Child Health Care) ; Dai-Juan Cheng ; BA ; MA (Research Student in Maternal ; Child Health Care) ; Pu-Yu Su ; BA ; MA (Lecturer in Maternal ; Child Health Care) ; Peng Zhu ; BA ; MA ; MD (Lecturer in Maternal ; Child Health Care) ; Yuan-Yuan Xu ; BA ; MA (Laboratory Assistant in Maternal ; Child Health Care) ; Ying Sun ; BA ; MA (Lecturer in Maternal ; Child Health Care)
• 关键词：Folic acid ; Supplementation ; Periconceptional ; Pregnant women
• 刊名：Midwifery
• 出版年：2012
• 期刊代码：224_02666138
• 类别：med
• 出版时间：June, 2012
• 卷：28
• 期：3
• 页码：291-297
• 文件大小：150 K

摘要

Objectives

to examine the rate of periconceptional and optimal folic acid supplementation, and to characterise their patterns and determinants among antenatal women in central China.

Design

data from 4290 women in the Anhui Birth Defects and Child Development Cohort Study recruited between October 2008 and September 2009 were analysed.

Setting

seven Maternal and Child Health Centres of two cities (Hefei and Maanshan) in Anhui province of central China.

Participants

women initiating prenatal care were included and asked to complete a structured questionnaire regarding folic acid supplementation.

Findings

sixty-eight per cent (2905/4290) of pregnant women reported taking folic acid supplementation periconceptionally (i.e. at some point before or during early pregnancy), and 32.8%(1405/4290) and 65.2%(2797/4290) had taken it before or during early pregnancy, respectively. However, only 16.1%(690/4290) used it optimally (i.e. regularly from four weeks before pregnancy throughout four weeks after pregnancy). Use of periconceptional folic acid was significantly associated with educational level, household income, registered residence, age, gestational age at recruitment, and planning of pregnancy.

Conclusion

optimal folic acid supplementation was relatively low.

Implications for practice

further efforts are needed to inform the population and promote the use of folic acid supplementation.