A new route for the synthesis of substituted 5-amino-4-cyanoimidazol-2-ones 鈥?precursors for the preparation of 3,6,7,9-tetrahydro-8H-purin-8-ones derivatives
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- 作者：S. A. Chumachenko (1)
O. V. Shablykin (1)
A. P. Kozachenko (1)
T. V. Osadchuk (1)
V. S. Brovarets (1) brovarets@bpci.kiev.ua - 关键词：5 ; alkyl(aryl)amino ; 2 ; oxoimidazole ; 4 ; thioamides – ; 5 ; alkyl(aryl)amino ; 4 ; cyanoimidazol ; 2 ; ones – ; 2 ; alkoxycarbonylamino ; 3 ; 3 ; dichloroacrylonitriles – ; 3 ; 6 ; 7 ; 9 ; tetrahydro ; 8H ; purin ; 8 ; ones – ; triethyl orthoformate – ; heterocyclization
- 刊名：Chemistry of Heterocyclic Compounds
- 出版时间：June 2011
- 出版年：2011
- 期刊代码：19_00093122
- 类别：mat
- 卷：47
- 期：3
- 页码：336-341
- 数据来源：sp
摘要
5-Alkyl(aryl)amino-4-cyanoimidazol-2-ones were obtained on the basis of 2-alkoxycarbonylamino-3,3-dichloroacrylonitriles. They were then used for the synthesis of derivatives of 3,6,7,9-tetrahydro-8H-purin-8-ones.