奚氏中医外科技术治疗糖尿病足溃疡180例临床疗效观察
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摘要
[目的]观察奚氏中医外科技术治疗糖尿病足溃疡的临床疗效。[方法]将符合纳入标准的糖尿病足溃疡患者随机分为治疗组90例和对照组90例,并根据溃疡的类型分为筋疽组、脱疽组分别对照。除常规全身系统治疗外,治疗组使用奚氏中医外科技术,对照组使用常规换药技术,换药每日1次。观察治疗前后的疗效指标、安全性指标,记录治疗过程中出现的不良反应。[结果]脱疽治疗组疮面愈合的总显效率为66.7%,脱疽对照组疮面愈合的总显效率为39.2%,两组比较差异有统计学意义(P<0.01)。筋疽治疗组疮面愈合的总显效率为76.2%,筋疽对照组疮面愈合的总显效率为46.2%,两组比较差异有统计学意义(P<0.05)。[结论]奚氏中医外科技术促进糖尿病足溃疡的疮面愈合的疗效确切。
[Objective] To observe the clinical effect of Xishi external treatment of traditional Chinese medicine on diabetic foot ulcer. [Methods] One hundred and eighty diabetic foot ulcer cases were randomized into treatment group of 90 cases and control group of 90 cases, while divided into diabetic foot anthrax group and diabetic foot tendons gangrene group according to the type of ulcer. Based on the basic treatment, the treatment group was administered Xishi external treatment of traditional Chinese medicine once a day, and the control group was administered Conventional dressing technology once a day. The index of curative effect and security before and after treatment were observed. Meanwhile record the adverse reactions during the treatment. [Results] Anthrax group: The total cure and remarkably effect rate of diabetic foot ulcer in treatment group is 66.7%. And the total cure and remarkably effect rate of diabetic foot ulcer in control group is 39.2%. Difference between the two groups has statistical significance(P<0.01). Tendons gangrene group: The total cure and remarkably effect rate of diabetic foot ulcer in treatment group is 76.2%. And the total cure and remarkably effect rate of diabetic foot ulcer in control group is 46.2%. Difference between the two groups has statistical significance(P<0.05). [Conclusion] Xishi external treatment of traditional Chinese medicine is effective for diabetic foot ulcer.
[Objective] To observe the clinical effect of Xishi external treatment of traditional Chinese medicine on diabetic foot ulcer. [Methods] One hundred and eighty diabetic foot ulcer cases were randomized into treatment group of 90 cases and control group of 90 cases, while divided into diabetic foot anthrax group and diabetic foot tendons gangrene group according to the type of ulcer. Based on the basic treatment, the treatment group was administered Xishi external treatment of traditional Chinese medicine once a day, and the control group was administered Conventional dressing technology once a day. The index of curative effect and security before and after treatment were observed. Meanwhile record the adverse reactions during the treatment. [Results] Anthrax group: The total cure and remarkably effect rate of diabetic foot ulcer in treatment group is 66.7%. And the total cure and remarkably effect rate of diabetic foot ulcer in control group is 39.2%. Difference between the two groups has statistical significance(P<0.01). Tendons gangrene group: The total cure and remarkably effect rate of diabetic foot ulcer in treatment group is 76.2%. And the total cure and remarkably effect rate of diabetic foot ulcer in control group is 46.2%. Difference between the two groups has statistical significance(P<0.05). [Conclusion] Xishi external treatment of traditional Chinese medicine is effective for diabetic foot ulcer.
引文
[1]国家中医药管理局.中医病证诊断疗效标准[S].北京:中国医药科技出版社,2012:140.
[2]Boulton AJ,Vileikute L,Raanarson-Tennval G,et al.The global burden of diabetic foot disease[J].Lancet,2005,366:1719-1724.
[3]Boulton AJ.The diabetic foot:grand overview,epidemiology and pathogenesis[J].Diabetes Metab Res Rev,2008,24(Suppll):S3-S6.
[4]奚九一,赵兆琳.糖尿病足肌腱变性坏死症(筋疽)的临床研究[J].上海中医药杂志,1996,30(5):1-3.
[5]杨婷,柳国斌.糖尿病足溃疡难愈的分子生物学机制研究现状[J].云南中医学院学报,2015,38(4):96-100.
[6]陆姿赢,王丽翔,柳国斌.中医外科特色技术治疗糖尿病足临床综述[J].浙江中医药大学学报,2014,38(5):664-666.
[7]李辉,金萌,唐乾利,等.糖尿病足溃疡的中医外治研究进展[J].中医烧伤创疡杂志,2015,27(2):108-111.
[8]陆姿赢,王丽翔,焦晶,等.紫朱软膏外用治疗下肢慢性皮肤溃疡72例临床疗效观察[J].浙江中医药大学学报,2015,39(4):289-291.
[2]Boulton AJ,Vileikute L,Raanarson-Tennval G,et al.The global burden of diabetic foot disease[J].Lancet,2005,366:1719-1724.
[3]Boulton AJ.The diabetic foot:grand overview,epidemiology and pathogenesis[J].Diabetes Metab Res Rev,2008,24(Suppll):S3-S6.
[4]奚九一,赵兆琳.糖尿病足肌腱变性坏死症(筋疽)的临床研究[J].上海中医药杂志,1996,30(5):1-3.
[5]杨婷,柳国斌.糖尿病足溃疡难愈的分子生物学机制研究现状[J].云南中医学院学报,2015,38(4):96-100.
[6]陆姿赢,王丽翔,柳国斌.中医外科特色技术治疗糖尿病足临床综述[J].浙江中医药大学学报,2014,38(5):664-666.
[7]李辉,金萌,唐乾利,等.糖尿病足溃疡的中医外治研究进展[J].中医烧伤创疡杂志,2015,27(2):108-111.
[8]陆姿赢,王丽翔,焦晶,等.紫朱软膏外用治疗下肢慢性皮肤溃疡72例临床疗效观察[J].浙江中医药大学学报,2015,39(4):289-291.