隔药灸脐配合腹针治疗原发性痛经的疗效观察
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摘要
目的观察隔药灸脐配合腹针治疗原发性痛经的临床疗效。方法将82例原发性痛经患者随机分为治疗组和对照组,每组41例。治疗组采用隔药灸脐配合腹针治疗,对照组采用单纯腹针治疗。观察两组治疗前后血清指标(PGE2、PGF2?含量)和彩色多普勒超声检查结果(PI、RI)的变化情况,并比较两组临床疗效。结果两组治疗后血清PGE2、PGF2?含量与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗后子宫动脉PI和RI与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗后血清中PGE2、PGF2?含量及子宫动脉PI和RI与对照组比较,差异均具有统计学意义(P<0.05)。治疗组总有效率为97.6%,对照组为82.9%,两组比较差异具有统计学意义(P<0.05)。结论隔药灸脐配合腹针治疗原发性痛经有助于改善患者子宫动脉血流状况和体内激素状况。
Objective To observe the clinical efficacy of herb-partitioned moxibustion at umbilicus plus abdominal acupuncture in treating primary dysmenorrhea. Method Eighty-two patients with primary dysmenorrhea were randomized into a treatment group and a control group, with 41 cases in each group. The treatment group was intervened by herb-partitioned moxibustion at umbilicus plus abdominal acupuncture, and the control group was treated with abdominal acupuncture alone. Before and after treatment, serum indexes [contents of prostaglandin E2(PGE2) and prostaglandin F2?(PGF2?)] and color Doppler ultrasonography [pulsatility index(PI) and resistance index(RI)] were observed, and the clinical efficacies of the two groups were compared. Result After treatment, the serum contents of PGE2 and PGF2? changed significantly in both groups(P<0.05). The PI and RI of uterine artery changed significantly after intervention in the treatment group(P<0.05). After treatment, the serum contents of PGE2 and PGF2? and the PI and RI of uterine artery in the treatment group were significantly different from those in the control group(P<0.05).The total effective rate was 97.6% in the treatment group, versus 82.9% in the control group, and the between-group difference was statistically significant(P< 0.05). Conclusion Herb-partitioned moxibustion at umbilicus plus abdominal acupuncture can help improve the blood flow of uterine artery and hormone levels in treating primary dysmenorrhea.
Objective To observe the clinical efficacy of herb-partitioned moxibustion at umbilicus plus abdominal acupuncture in treating primary dysmenorrhea. Method Eighty-two patients with primary dysmenorrhea were randomized into a treatment group and a control group, with 41 cases in each group. The treatment group was intervened by herb-partitioned moxibustion at umbilicus plus abdominal acupuncture, and the control group was treated with abdominal acupuncture alone. Before and after treatment, serum indexes [contents of prostaglandin E2(PGE2) and prostaglandin F2?(PGF2?)] and color Doppler ultrasonography [pulsatility index(PI) and resistance index(RI)] were observed, and the clinical efficacies of the two groups were compared. Result After treatment, the serum contents of PGE2 and PGF2? changed significantly in both groups(P<0.05). The PI and RI of uterine artery changed significantly after intervention in the treatment group(P<0.05). After treatment, the serum contents of PGE2 and PGF2? and the PI and RI of uterine artery in the treatment group were significantly different from those in the control group(P<0.05).The total effective rate was 97.6% in the treatment group, versus 82.9% in the control group, and the between-group difference was statistically significant(P< 0.05). Conclusion Herb-partitioned moxibustion at umbilicus plus abdominal acupuncture can help improve the blood flow of uterine artery and hormone levels in treating primary dysmenorrhea.
引文
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[11]刘鸿燕,朱欢.腹针结合热敏灸治疗寒凝血瘀型原发性痛经30例总结[J].湖南中医杂志,2017,33(8):96-97.
[12]刘常胜,冯玉山,何孟泽.针刺结合艾灸关元穴治疗原发性痛经的临床研究[J].中医临床研究,2017,9(13):40-41.
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[14]黄冬梅,司瑞超.艾灸治疗原发性痛经随机平行对照研究[J].实用中医内科杂志,2017,31(2):20-21.
[15]Valedi S,Alimoradi Z,MoradiBaglooei M,et al.Investigating the effect of Eye Movement Desensitization and Reprocessing on pain intensity in patients with primary dysmenorrhea:a protocol for a randomized controlled trial[J].Trials,2019,20(1):404.
[16]Hu NJ,Liu YQ,Zhao MY,et al.Influence of the Intensity Components,and Spreading of the Deqi Sensation on the Analgesic Effect of SP6 Needling in Primary Dysmenorrhea Patients:A Secondary Analysis of a Randomised Controlled Trial[J].Evid Based Complement Alternat Med,2019,2019:6462576.
[17]Bajalan Z,Moafi F,MoradiBaglooei M,et al.Mental health and primary dysmenorrhea:a systematic review[J].J Psychosom Obstet Gynaecol,2018,5:1-10.
[18]Barassi G,Bellomo RG,Porreca A,et al.Somato-visceral effects in the treatment of dysmenorrhea:neuromuscular manual therapy and standard pharmacological treatment[J].J Altern Complement Med,2018,24(3):291-299.
[19]谢洪武,刘福水,焦琳,等.热敏灸治疗原发性痛经及经期常见伴随症状的临床疗效观察[J].时珍国医国药,2016,27(9):2187-2189.
[20]杨娇,郭锡全.神阙敷贴法治疗血瘀型原发性痛经疗效观察[J].上海针灸杂志,2017,36(2):162-166.
[21]袁晓明,文豪,谢秩芬,等.推拿配合热动力灸治疗原发性痛经[J].山西中医,2016,32(9):32-33.
[22]谢秀俊,朱希法,陈日新,等.温和灸不同状态关元穴治疗原发性痛经非随机对照研究[J].上海针灸杂志,2018,37(8):895-899.
[23]Geoffron S,Cohen J,Sauvan M,et al.Endometriosis medical treatment:hormonal treatment for the management of pain and endometriotic lesions recurrence.CNGOF-HAS Endometriosis Guidelines[J].Gynecol Obstet Fertil Senol,2018,46(3):231-247.
[24]阮春鑫,林树梁,陈兴奎,等.药物铺灸治疗寒湿凝滞型原发性痛经及对患者子宫动脉血流的影响[J].中国针灸,2016,36(8):827-830.
[25]Lang L,Meng Z,Sun L,et al.Intergrated metabonomic study of the effects of Guizhi Fuling capsule intervention on primary dysmenorrheal using RP-UPLC-MScomplementary with HILIC-UPLC-MS technique[J].Biomed Chromatogr,2018,32(2):4093.
[26]刘照时,黄月娜,赵苏萍,等.隔药灸治疗前后不同证型原发性痛经患者生殖激素水平检测研究[J].中国妇幼保健,2016,31(4):779-781.
[2]黄奏琴,田甜,蔡勤华,等.多功能艾灸仪隔药灸治疗原发性痛经疗效观察[J].上海针灸杂志,2018,37(4):378-381.
[3]郝仓仓,王昕.针灸治疗寒凝血瘀型原发性痛经疗效观察[J].中华中医药学刊,2018,36(3):659-662.
[4]乐杰.妇产科学[M].第6版.北京:人民卫生出版社,2013:347.
[5]Neri M,Piras B,Paoletti AM,et al.Long-acting reversible contraception(LARC)with the intrauterine system with levonorgestrel(6?mcg/d):observational study on the acceptability,quality of life,and sexuality in Italian women[J].Gynecol Endocrinol,2018,34(6):532-535.
[6]叶彩凤,李辉.温灸及经皮电刺激对原发性痛经情绪改善的影响[J].现代临床医学,2018,44(1):19-21.
[7]安应成.隔药灸联合腹针治疗原发性痛经随机平行对照研究[J].实用中医内科杂志,2017,31(12):55-58.
[8]高艳霞.隔中药穴位艾灸治疗高校女生原发性痛经疗效观察[J].中医药临床杂志,2017,29(10):1722-1724.
[9]Erdem S,Imboden S,Papadia A,et al.Functional outcomes after rectal resection for deep infiltrating pelvic endometriosis:long-term results[J].Dis Colon Rectum2018,61(6):733-742.
[10]冯雯,张彤,盖云.三伏贴联合督脉灸治疗寒凝血瘀型痛经临床疗效观察[J].天津中医药,2017,34(9):595-597.
[11]刘鸿燕,朱欢.腹针结合热敏灸治疗寒凝血瘀型原发性痛经30例总结[J].湖南中医杂志,2017,33(8):96-97.
[12]刘常胜,冯玉山,何孟泽.针刺结合艾灸关元穴治疗原发性痛经的临床研究[J].中医临床研究,2017,9(13):40-41.
[13]Wei Y,Ma T,Wang H,et al.Extracts of compound Muniziqi granule suppressed uterus contraction and ameliorated oxytocin-induced primary dysmenorrhea[J].J Ethnopharmacol,2018,223:33-40.
[14]黄冬梅,司瑞超.艾灸治疗原发性痛经随机平行对照研究[J].实用中医内科杂志,2017,31(2):20-21.
[15]Valedi S,Alimoradi Z,MoradiBaglooei M,et al.Investigating the effect of Eye Movement Desensitization and Reprocessing on pain intensity in patients with primary dysmenorrhea:a protocol for a randomized controlled trial[J].Trials,2019,20(1):404.
[16]Hu NJ,Liu YQ,Zhao MY,et al.Influence of the Intensity Components,and Spreading of the Deqi Sensation on the Analgesic Effect of SP6 Needling in Primary Dysmenorrhea Patients:A Secondary Analysis of a Randomised Controlled Trial[J].Evid Based Complement Alternat Med,2019,2019:6462576.
[17]Bajalan Z,Moafi F,MoradiBaglooei M,et al.Mental health and primary dysmenorrhea:a systematic review[J].J Psychosom Obstet Gynaecol,2018,5:1-10.
[18]Barassi G,Bellomo RG,Porreca A,et al.Somato-visceral effects in the treatment of dysmenorrhea:neuromuscular manual therapy and standard pharmacological treatment[J].J Altern Complement Med,2018,24(3):291-299.
[19]谢洪武,刘福水,焦琳,等.热敏灸治疗原发性痛经及经期常见伴随症状的临床疗效观察[J].时珍国医国药,2016,27(9):2187-2189.
[20]杨娇,郭锡全.神阙敷贴法治疗血瘀型原发性痛经疗效观察[J].上海针灸杂志,2017,36(2):162-166.
[21]袁晓明,文豪,谢秩芬,等.推拿配合热动力灸治疗原发性痛经[J].山西中医,2016,32(9):32-33.
[22]谢秀俊,朱希法,陈日新,等.温和灸不同状态关元穴治疗原发性痛经非随机对照研究[J].上海针灸杂志,2018,37(8):895-899.
[23]Geoffron S,Cohen J,Sauvan M,et al.Endometriosis medical treatment:hormonal treatment for the management of pain and endometriotic lesions recurrence.CNGOF-HAS Endometriosis Guidelines[J].Gynecol Obstet Fertil Senol,2018,46(3):231-247.
[24]阮春鑫,林树梁,陈兴奎,等.药物铺灸治疗寒湿凝滞型原发性痛经及对患者子宫动脉血流的影响[J].中国针灸,2016,36(8):827-830.
[25]Lang L,Meng Z,Sun L,et al.Intergrated metabonomic study of the effects of Guizhi Fuling capsule intervention on primary dysmenorrheal using RP-UPLC-MScomplementary with HILIC-UPLC-MS technique[J].Biomed Chromatogr,2018,32(2):4093.
[26]刘照时,黄月娜,赵苏萍,等.隔药灸治疗前后不同证型原发性痛经患者生殖激素水平检测研究[J].中国妇幼保健,2016,31(4):779-781.