基于属性偏序结构图对《妇人大全良方》中治疗胎停育相关方药分析
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摘要
目的分析、总结《妇人大全良方》中治疗胎停育相关方药的用药特点,以期为临床治疗提供思路与参考依据。方法筛选出《妇人大全良方》中58首治疗胎停育的方剂,共涉及101味中药,基于形式概念分析理论,建立形式背景,生成方药属性偏序结构图,客观、全面地展示方药配伍规律。结果从上到下,从左到右观察结构图,由第一层与第二层可见出现频次较高的药物有当归、酒、阿胶、甘草、大枣、葱白、肉桂、牛膝、川芎、艾叶、熟地,反复出现的药物组合有当归与川芎,当归与熟地,阿胶与艾叶,当归、川芎与阿胶。结论《妇人大全良方》中与胎停育相关证候的治疗方剂重视气血,选药以辛热温散为主,主要治法有以血为本,气血并治;温经通络,以行气血;补养脾胃,以生气血;下胎时注重通行血脉,以防留瘀。
Objective It is to analysis and summed up the characteristics of Chinese medicine treatment of ovum blighted in the"Furen Daquan Liang Fang"in order to provide ideas and reference for the clinical treatment. Methods 58 Chinese medicine prescriptions for ovum blighted were collected from "Furen Daquan Liang Fang",involved 101 Chinese herbs. Then,generating a partial-order attribute diagram based on formal concept analysis(FCA) in order to present the specific character and to explain properties of partial order structure graph from structural partial-ordered attribute diagram,which was systematic,objective and comprehensive. Results From top to bottom,from left to right to observe the structure diagram of prescriptions,by the first layer and the second layer a higher frequency of drugs were found respectively,which were Danggui,Wine,Ejiao,Gancao,Dazao,Congbai,Rougui,Niuxi,Chuanxiong,Aiye,Shudi,and 4 repeated drug combinations were found respectively,which were Danggui and Chuanxiong,Danggui and Shudi,Ejiao and Aiye,Danggui Chuanxiong and Ejiao. Conclusion In"Furen Daquan Liang Fang",the prescriptions pay attention to Qi and blood in the treatment of ovum blighted,mainly chooses herbs with divergence and warm. There are 4 main treatment methods:blood-based and regulated the movement of Qi and blood; pass network with a warm to circulate Qi and blood; raise spleen and stomach to produce Qi and blood; have an abortion with loosing of stimulate the menstrual flow to prevent producing stagnant blood.
Objective It is to analysis and summed up the characteristics of Chinese medicine treatment of ovum blighted in the"Furen Daquan Liang Fang"in order to provide ideas and reference for the clinical treatment. Methods 58 Chinese medicine prescriptions for ovum blighted were collected from "Furen Daquan Liang Fang",involved 101 Chinese herbs. Then,generating a partial-order attribute diagram based on formal concept analysis(FCA) in order to present the specific character and to explain properties of partial order structure graph from structural partial-ordered attribute diagram,which was systematic,objective and comprehensive. Results From top to bottom,from left to right to observe the structure diagram of prescriptions,by the first layer and the second layer a higher frequency of drugs were found respectively,which were Danggui,Wine,Ejiao,Gancao,Dazao,Congbai,Rougui,Niuxi,Chuanxiong,Aiye,Shudi,and 4 repeated drug combinations were found respectively,which were Danggui and Chuanxiong,Danggui and Shudi,Ejiao and Aiye,Danggui Chuanxiong and Ejiao. Conclusion In"Furen Daquan Liang Fang",the prescriptions pay attention to Qi and blood in the treatment of ovum blighted,mainly chooses herbs with divergence and warm. There are 4 main treatment methods:blood-based and regulated the movement of Qi and blood; pass network with a warm to circulate Qi and blood; raise spleen and stomach to produce Qi and blood; have an abortion with loosing of stimulate the menstrual flow to prevent producing stagnant blood.
引文
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[15]沈怡华,赵岩松.胎停育中西医认识及现状评述[J].现代中西医结合杂志,2015,24(29):3300-3303
[2]严仁英.妇产科学辞典[M].北京:北京科学技术出版社,2003:570
[3]唐仕欢,杨洪军.中医组方用药规律研究进展述评[J].中国实验方剂学杂志,2013,19(5):359-363
[4]潘建科,何於,刘军,等.基于属性偏序结构图)方法的膝骨关节炎熏洗处方用药规律研究[J].中华中医药杂志,2014,29(5):1677-1681
[5]刘超男,徐笋晶,李赛美,等.基于多层次复杂概念网络表示方法的《伤寒论》方药按治法分类的知识发现[J].北京中医药大学学报,2014,37(7):452-457
[6]樊凤杰,洪文学.基于属性偏序结构图表示原理的中药方剂配伍规律研究[J].生物医学工程学杂志,2013,30(4):719-723
[7]洪文学,栾景民,张涛,等.基于偏序结构理论的知识发现方法[J].燕山大学学报,2014,38(5):394-402
[8]屈华,李赛美,洪文学,等.基于多层次复杂概念网络表示原理的《伤寒论》群结构知识发现方法研究[J].中华中医药杂志,2013,28(5):1241-1246
[9]徐笋晶,李赛美,洪文学,等.基于形式概念分析数学理论的经方诊治情志病证治规律研究[J].世界科学技术-中医药现代化,2014,16(9):2025-2030
[10]高学敏.中药学[M].北京:中国中医药出版社,2010
[11]屈华,李赛美,洪文学,等.基于多层次复杂概念网络表示原理的《伤寒论》群结构知识发现方法研究[J].中华中医药杂志,2013,28(5):1241-1246
[12]唐慎微.证类本草[M].北京:中国医药科技出版社,2011
[13]Mc Lachlan RI,O'Bryan MK.Clinical review:state of the art for genetic testing of infertile men[J].J Clin Endocrinol Metab,2010,95(3):1013-1024
[14]马立新,刘旦旦.超声诊断早期胚胎停育[J].中国优生与遗传杂志,2014,22(5):88-89
[15]沈怡华,赵岩松.胎停育中西医认识及现状评述[J].现代中西医结合杂志,2015,24(29):3300-3303