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幽门螺杆菌黏附素及其致病作用的研究进展
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  • 英文篇名:Research progress of Helicobacter pylori adhesin and its pathogenic effect
  • 作者:黄秋月 ; 叶晖 ; 于靖 ; 张学智
  • 英文作者:HUANG Qiuyue;YE Hui;YU Jing;ZHANG Xuezhi;Department of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital;
  • 关键词:幽门螺杆菌 ; 黏附素 ; 黏附受体 ; 致病
  • 英文关键词:Helicobacter pylori;;Adhesin;;Adhesion receptor;;Pathogenicity
  • 中文刊名:WCBX
  • 英文刊名:Chinese Journal of Gastroenterology and Hepatology
  • 机构:北京大学第一医院中西医结合科;
  • 出版日期:2019-05-20
  • 出版单位:胃肠病学和肝病学杂志
  • 年:2019
  • 期:v.28
  • 基金:国家自然科学基金面上项目(81473474);; 北京市自然科学基金面上项目(7172220)
  • 语种:中文;
  • 页:WCBX201905019
  • 页数:5
  • CN:05
  • ISSN:41-1221/R
  • 分类号:89-93
摘要
幽门螺杆菌(Helicobacter pylori,H. pylori)黏附素是由H. pylori表达并参与H. pylori对胃黏膜的黏附、定植的一种外膜蛋白。这些黏附素不仅参与对胃黏膜的黏附、定植,还与H. pylori的持续感染和疾病的严重程度密切相关。该文结合近几年国内外文献,对H. pylori黏附素、黏附受体及其致病作用的研究进展作一概述。
        Helicobacter pylori(H. pylori) adhesin is a kind of outer membrane proteins expressed by H. pylori and involved in the adhesion and colonization to gastric mucosa. These adhesins not only participate in the adhesion and colonization to gastric mucosa, but also are closely related to the persistence of infection and the severity of the disease. In this paper, the recent research progresses of H. pylori adhesin, adhesion receptor and their pathogenic effect were.
引文
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