专项点评干预对我院辅助用药合理应用的影响
|
摘要
目的规范辅助用药的临床使用。方法确定2016年我院销售金额排名前10位的辅助用药,利用循证医学证据逐一建立点评标准,自2017年1月开始进行专项点评及干预。分别选取2016年5-12月(专项点评干预前)与2017年1-8月(专项点评干预后)使用这10种辅助用药的病历各4 000份,比较其点评干预前后的应用情况。结果专项点评干预后,不合理现象比例均明显减少,包括适应证不适宜、溶媒不适宜、联合用药不适宜、用法用量不适宜、重复用药、疗程过长及用药禁忌等,排名前10位的辅助用药占所有辅助用药销售金额的比例由干预前的39.98%降至干预后的31.62%。结论我院初步建立的辅助用药点评方式有效促进了其在临床上的合理使用。
Objective To standardize the clinical use of adjuvant medications. Methods The top 10 adjuvant medications in the list of consumption sum in 2016 were collected and summarized. The criteria were established by use of evidence-based medical evidence,and targeted intervention was implemented from January 2017. Totally 4 000 medical records in each group of the top 10 adjuvant medications were selected from May to December 2016( pre-special comment group) and from January to August 2017( post-special comment group). The application of the top 10 adjuvant medications were compared before and after comments and targeted intervention. Results After special comments and intervention,the ratio of irrational drug use was significantly decreased,including improper indication,inappropriate solvents,improper combination,irrational dosage,repeated drug application,irrational treatment course and drug contraindication. The ratio in sales amount of top 10 adjuvant medications to all adjuvant medications was reduced from 39. 98% to 31. 62%. Conclusion The established comment mode of adjuvant medications in our hospital has effectively improved rational clinical drug use.
Objective To standardize the clinical use of adjuvant medications. Methods The top 10 adjuvant medications in the list of consumption sum in 2016 were collected and summarized. The criteria were established by use of evidence-based medical evidence,and targeted intervention was implemented from January 2017. Totally 4 000 medical records in each group of the top 10 adjuvant medications were selected from May to December 2016( pre-special comment group) and from January to August 2017( post-special comment group). The application of the top 10 adjuvant medications were compared before and after comments and targeted intervention. Results After special comments and intervention,the ratio of irrational drug use was significantly decreased,including improper indication,inappropriate solvents,improper combination,irrational dosage,repeated drug application,irrational treatment course and drug contraindication. The ratio in sales amount of top 10 adjuvant medications to all adjuvant medications was reduced from 39. 98% to 31. 62%. Conclusion The established comment mode of adjuvant medications in our hospital has effectively improved rational clinical drug use.
引文
[1]韩爽,钟敏涛,李锦,等.我国辅助用药应用现状及管理对策初探[J].中国药学杂志,2016,51(8):678-682.
[2]黄光英,蔡小利,钱青.我院急诊科2014年1-6月辅助治疗药物应用分析[J].中国药房,2015,26(11):1470-1472.
[3]General Office of the State Council.Guiding opinions of the general office of the State Council on improving the work of centralized procurement of drugs in public hospitals[EB/OL].2015[2015-10-21].http://www.Gov.cn/zhengce/content/2015-02/28/content_9502.htm.
[4]上海第一生化药业有限公司.注射用二丁酰环磷腺苷钙[S].2006-12-27.
[5]广东省药学会.肠外营养临床药学共识[J].今日药学,2016,26(1):1.
[6]中华医学会肠外肠内营养学分会,北京医学会肠外肠内营养学分会.维生素制剂临床应用专家共识[J].中华外科杂志,2015,53(7):481-487.
[7]洪远,叶建林,殷建忠,等.转化糖电解质注射液与7种临床常用药配伍禁忌分析[J].药学与临床研究,2013,21(5):570-571.
[8]高田田,孙超,冷冰,等.钠钾镁钙葡萄糖注射液临床使用合理性及安全性分析[J].中国药物应用与监测,2017,14(4):240-242.
[9]刘宏明,许莉莉,崔冉,等.66例醒脑静注射液不良反应的文献分析[J].中国药物警戒,2016,13(2):107-110.
[10]刘福香,朱红燕.多种微量元素注射液与注射用辅酶A、注射用12种复合维生素存在配伍禁忌[J].医药与保健,2014,22(8):74.
[11]王晶,张丹丹,卜晓翠.前列地尔两种给药途径对静脉炎发生率的影响[J].中国继续医学教育,2017,9(2):186-188.
[12]郑斌,刘茂柏,陈灵屹.急性缺血性脑卒中不同品种数辅助药物治疗方案的成本-效果分析[J].海峡药学,2014,26(8):137-139.
[13]山西普德药业股份有限公司.注射用12种复合维生素[S].2014-05-29.
[14]Jia G,Aroor AR,Whaley-Connell AT,et al.Fructose and uric acid:is there a role in endothelial function[J].Curr Hypertens Rep,2014,16(6):434.
[15]吴俊,顾敏,宋楷,等.抗肿瘤辅助药物管理系统开发应用[J].中国数字医学,2013,8(2):14-16.
[2]黄光英,蔡小利,钱青.我院急诊科2014年1-6月辅助治疗药物应用分析[J].中国药房,2015,26(11):1470-1472.
[3]General Office of the State Council.Guiding opinions of the general office of the State Council on improving the work of centralized procurement of drugs in public hospitals[EB/OL].2015[2015-10-21].http://www.Gov.cn/zhengce/content/2015-02/28/content_9502.htm.
[4]上海第一生化药业有限公司.注射用二丁酰环磷腺苷钙[S].2006-12-27.
[5]广东省药学会.肠外营养临床药学共识[J].今日药学,2016,26(1):1.
[6]中华医学会肠外肠内营养学分会,北京医学会肠外肠内营养学分会.维生素制剂临床应用专家共识[J].中华外科杂志,2015,53(7):481-487.
[7]洪远,叶建林,殷建忠,等.转化糖电解质注射液与7种临床常用药配伍禁忌分析[J].药学与临床研究,2013,21(5):570-571.
[8]高田田,孙超,冷冰,等.钠钾镁钙葡萄糖注射液临床使用合理性及安全性分析[J].中国药物应用与监测,2017,14(4):240-242.
[9]刘宏明,许莉莉,崔冉,等.66例醒脑静注射液不良反应的文献分析[J].中国药物警戒,2016,13(2):107-110.
[10]刘福香,朱红燕.多种微量元素注射液与注射用辅酶A、注射用12种复合维生素存在配伍禁忌[J].医药与保健,2014,22(8):74.
[11]王晶,张丹丹,卜晓翠.前列地尔两种给药途径对静脉炎发生率的影响[J].中国继续医学教育,2017,9(2):186-188.
[12]郑斌,刘茂柏,陈灵屹.急性缺血性脑卒中不同品种数辅助药物治疗方案的成本-效果分析[J].海峡药学,2014,26(8):137-139.
[13]山西普德药业股份有限公司.注射用12种复合维生素[S].2014-05-29.
[14]Jia G,Aroor AR,Whaley-Connell AT,et al.Fructose and uric acid:is there a role in endothelial function[J].Curr Hypertens Rep,2014,16(6):434.
[15]吴俊,顾敏,宋楷,等.抗肿瘤辅助药物管理系统开发应用[J].中国数字医学,2013,8(2):14-16.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |