摘要
目的:对养阴生津片治疗气阴两虚证甲状腺功能亢进症的临床效果作探讨。方法:选择我院2015年1月-2017年12月收治的气阴两虚证甲状腺功能亢进症患者60例作研究对象,将其根据随机数字表法均分组为对照组30例用他巴唑治疗,观察组30例用他巴唑+养阴生津片治疗;将两组患者临床治疗效果作对比分析。结果:治疗后两组患者中医证候积分数值均见降低,但观察组患者咽干口燥、五心烦热、心悸心慌、失眠/多梦、夜寐盗汗、气短乏力、纳少自汗、便溏/次数增多等中医证候积分数值明显低于对照组,P <0.05;治疗前两组患者促甲状腺激素(Thyroid Stimulating Hormone,TSH)、游离三碘甲腺原氨酸(FT3)、游离甲状腺素(FT4)水平比较差异无有统计学意义,P> 0.05;治疗后两组患者TSH、FT3、FT4水平均见改变,但观察组患者TSH、FT3、FT4水平改变程度明显优于对照组,P <0.05;观察组临床治疗总有效率(96.70%)比对照组(73.30%)高,P <0.05;两组患者不良事件发生率比较差异无统计学意义,P> 0.05。结论:气阴两虚证甲状腺功能亢进症患者选择养阴生津片辅助治疗的效果更佳。
Objective: To investigate the clinical effect of the Yangyin Shengjin tablets( 养 阴 生 津 片) on hyperthyroidism with the Qiyin Liangxu syndrome( 气 阴 两 虚 证). Methods: 60 patients were grouped. 30 patients in the control group were treated with tazobactam. 30 patients in the observation group were treated with the Yangyin Shengjin tablets more. Results: After treatment, the TCM syndrome scores in two groups were reduced, and those in the observation group were lower, P<0.05. After treatment, TSH, FT3 and FT4 were improved in two groups. and those in the observation group were significantly better, P<0.05. The total effective rate in the treatment group(96.7%) was higher than 73.3% in the control group, P<0.05. There was no difference in the incidence of adverse events between two groups, P>0.05. Conclusion: The Yangyin Shengjin tablets showed better effects on hyperthyroidism with the Qiyin Liangxu syndrome.
引文
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[2]余会丽.中西医结合治疗甲状腺功能亢进症临床疗效观察[J/CD].转化医学电子杂志,2015,2(04):99-100.
[3]张操,黄文霞,王丽云.中医辨证治疗甲状腺功能亢进症疗效分析[J].亚太传统医药,2016,12(22):106-108.