鸡矢藤中环烯醚萜苷类提取工艺研究现状
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摘要
鸡矢藤是传统中药,现代研究表明其中的环烯醚萜苷类具有较强的镇痛作用,其独特的化学结构和药理作用已引起人们的关注。文章从鸡矢藤中有效成分提取方法和环烯醚萜苷类的纯化富集方法两方面对鸡矢藤中环烯醚萜苷类的研究现状进行总结,为鸡矢藤中环烯醚萜苷类的开发利用提供参考依据,也为其进一步研究提供基础。
Paederia Scandens is a traditional Chinese medicine. The present studies have found that the Iridoid Glycosides of Paederia scandens has strong analgesic effect. Its special chemical structure and pharmacological action has drawn many researchers' attention. The paper summarized the present situation of studies on Paederia Scandens from the follow two aspects: the current extraction method for active ingredients of Paederia scandens and the current purification and beneficiation technology for Iridoid Glycosides of Paederia scandens. Thus, it can provide references for the further study or development and utilization on Iridoid Glycosides of Paederia scandens.
Paederia Scandens is a traditional Chinese medicine. The present studies have found that the Iridoid Glycosides of Paederia scandens has strong analgesic effect. Its special chemical structure and pharmacological action has drawn many researchers' attention. The paper summarized the present situation of studies on Paederia Scandens from the follow two aspects: the current extraction method for active ingredients of Paederia scandens and the current purification and beneficiation technology for Iridoid Glycosides of Paederia scandens. Thus, it can provide references for the further study or development and utilization on Iridoid Glycosides of Paederia scandens.
引文
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[4]杨勇.鸡矢藤挥发油的提取及化学成分的研究[J].陕西能源职业技术学院学报,2006(2):32-34.
[5]马养民,毛远,傅建熙.鸡矢藤挥发油化学成分的研究[J].西北植物学报,2000,20(1):145-148.
[6]王绍云.DNS法测定鸡屎藤中总糖含量的研究[J].中国调味品,2013,38(11):59-62,69.
[7]叶陈丽,林敏,郑超宾,等.超声波提取鸡矢藤总黄酮优化工艺研究[J].化学工程与装备,2010(3):37-39.
[8]刘晓燕,李彬.绵阳鸡屎藤中总黄酮的提取及含量测定[J].安徽农业科学,2015,43(22):66-68,72.
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[10]李杰.超临界CO2萃取鸡矢藤中有效成分的工艺研究[D].郑州大学,2012.
[11]李茂星,贾正平,张汝学,等.秦艽中裂环烯醚萜苷类成分的分离纯化研究[J].中成药,2005,27(12):1384-1386.
[12]李茂星,贾正平,胡之德,等.大孔树脂富集纯化藏药独一味总环烯醚萜苷[J].中国中药杂志,2007,32(17):1743-1747.
[13]余晓晖,赵磊,王谨慧,等.黄管秦艽中总裂环烯醚萜的大孔树脂纯化工艺研究[J].时珍国医国药,2010,21(12):3179-3180.
[14]才谦,刘涛,付玉芹,等.大孔吸附树脂法富集龙胆中裂环烯醚萜苷类成分的实验研究[J].中成药,2003,25(4):271-272.
[15]徐泽红,才谦.秦艽中裂环环烯醚萜苷类成分的纯化工艺研究[J].药物研究,2008,5(7):28-29.
[16]丁霞,余宗亮,杜伟峰,等.SP825-大孔树脂富集山茱萸环烯醚萜苷的工艺研究[J].中成药,2008,30(1):53-56.
[17]蔡黎明,周莹,蔡宝昌,等.不同大孔树脂富集山茱萸中环烯醚萜苷的效果比较[J].中国实验方剂学杂志,2013,19(13):39-41.
[18]谭玉琴,山光强,陈志刚,等.鸡屎藤的化学成分、提取工艺与药理作用研究进展[J].中兽医医药杂志,2016(1):18-21.
[2]Inouye H,Inouye S,Shimokawa N,et al.Iridoid glucosides from paederia scandens[J].Tetrahedron Lett,1968,9(6):683-688.
[3]Kapadia G J,Sharma S C,Tokuda H,et al.Inhibitory effect of iridoids on Epstein-Barr virus activation by a short-term in vitro assay for anti-tumor promoters[J].Cancer Letters,1996,102:223-226.
[4]杨勇.鸡矢藤挥发油的提取及化学成分的研究[J].陕西能源职业技术学院学报,2006(2):32-34.
[5]马养民,毛远,傅建熙.鸡矢藤挥发油化学成分的研究[J].西北植物学报,2000,20(1):145-148.
[6]王绍云.DNS法测定鸡屎藤中总糖含量的研究[J].中国调味品,2013,38(11):59-62,69.
[7]叶陈丽,林敏,郑超宾,等.超声波提取鸡矢藤总黄酮优化工艺研究[J].化学工程与装备,2010(3):37-39.
[8]刘晓燕,李彬.绵阳鸡屎藤中总黄酮的提取及含量测定[J].安徽农业科学,2015,43(22):66-68,72.
[9]林雪容,殷希,王艳艳,等.微波辅助提取鸡屎藤茎挥发油及其成分分析[J].安徽农业科学,2011,39(32):19738-19739.
[10]李杰.超临界CO2萃取鸡矢藤中有效成分的工艺研究[D].郑州大学,2012.
[11]李茂星,贾正平,张汝学,等.秦艽中裂环烯醚萜苷类成分的分离纯化研究[J].中成药,2005,27(12):1384-1386.
[12]李茂星,贾正平,胡之德,等.大孔树脂富集纯化藏药独一味总环烯醚萜苷[J].中国中药杂志,2007,32(17):1743-1747.
[13]余晓晖,赵磊,王谨慧,等.黄管秦艽中总裂环烯醚萜的大孔树脂纯化工艺研究[J].时珍国医国药,2010,21(12):3179-3180.
[14]才谦,刘涛,付玉芹,等.大孔吸附树脂法富集龙胆中裂环烯醚萜苷类成分的实验研究[J].中成药,2003,25(4):271-272.
[15]徐泽红,才谦.秦艽中裂环环烯醚萜苷类成分的纯化工艺研究[J].药物研究,2008,5(7):28-29.
[16]丁霞,余宗亮,杜伟峰,等.SP825-大孔树脂富集山茱萸环烯醚萜苷的工艺研究[J].中成药,2008,30(1):53-56.
[17]蔡黎明,周莹,蔡宝昌,等.不同大孔树脂富集山茱萸中环烯醚萜苷的效果比较[J].中国实验方剂学杂志,2013,19(13):39-41.
[18]谭玉琴,山光强,陈志刚,等.鸡屎藤的化学成分、提取工艺与药理作用研究进展[J].中兽医医药杂志,2016(1):18-21.