耳牙综合征
摘要
<正>牙齿发育异常是指牙齿数目异常、牙齿形态异常、牙齿结构异常、牙齿萌出与脱落异常。临床常见的牙齿形态异常有:畸形牙尖、畸形牙窝、过小牙、过大牙、双牙畸形和牙髓腔异常等等~([1])。球形牙齿是一种比较罕见的牙齿形态异常,1969年Denes和Csiba~([2])第一次在一位母亲和他儿子身上发现这种牙
引文
1葛立宏.儿童口腔医学.第四版.北京:人民卫生出版社,2012.69-81.
2 Denes J,Csiba A.An unusual case of hereditary developmental anomalies of cuspids and molars.Fogorv Sz,1969,62(7):208-212.
3 Toledo OA de,Bausells HI,Vono RM,et al.Multiple dental anomaly in three brothers,Case report.Rev Fac Farm Odontol Araraquara,1971,5:207-214.
4 Levin LS,Jorgenson RJ.Familial otodentodysplasia:a“new”syndrome.Am J Hum Genet,1972,24:61A.
5 Levin LS,Jorgenson RJ,Cook RA.Otodental dysplasia:a‘new’ectodermal dysplasia.Clin Genet,1975,8(2):136-144.
6 Witkop CJ Jr,Gundlach KK,Streed WJ,et al.Globodontia in the otodental syndrome.Ora Surg Oral Med Oral Pathol,1976,41(4):472-483.
7 Bloch-Zupan A.The portal for rare diseases and prphan drugs.“Ophanet:Otodental Syndrome.2014 MAR Http://www.orpha.net/consor/cgi-bin/OC_Exo.php?lng=en&Expert=2791
8 Winter GB.The association of ocular defects with the otodontal syndrome.J Int Assoc Dent Child,1983,14(2):83-87.
9 Vieira H,Gregory-Evans K,Lim N,et al.First genomic localization of oculo-oto-dental syndrome with linkage to chromosome 20q13.1.Invest Ophthalmol Vis Sci,2002,43(8):2540-2545.
10 Santos-Pinto L,Oviedo MP,Santos-Pinto A,et al.Otodental syndrome:three familial case reports.Pediatr Dent,1998,20(3):208-211.
11 Sedano HO,Moreira LC,de Souza RA,et al.Otodental syndrome:a case report and genetic considerations.Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2001,92(3):312-317.
12 Stewart DJ,Kinirons MJ.Globodontia.Ararely reported dental anormaly.Br Dent J,1982,152(8):287-288.
13 Enright S,Humphrys AK,Rea G,et al.Globodontia in the otodental syndrome:A Rare Defect of Tooth Morphology Occurring with Hearing Loss in An Eight-Year-Old.Dent Update,2015,42(10):927-930,932.
14 Gundlach KK,Witkop CJ Jr.Globodontia-a new familial tooth abnormality.Dtsch Zahnarztl,1977,32(2):194-196.
15 Mesaros AJ Jr,Basden JW.Otodental syndrome.Gen Dent,1996,44(5):427-429.
16 Beck-Mannagetta J,Muller H,Richter E,et al.Odontomas and pan-tonal hearing loss in the otodental syndrome.Dtsch Zahnazil Z,1984,39(3):232-241.
17 Van Doome L,Wackens G,De Maeseneer M,et al.Otodental syndrome:A Case report.Int J Oral Maxillofac Surg,1998,27(2):121-124.
18 Cehreli SB,Brannon RB,Musselman RJ,et al.Otodental syndrome:a case presentation in a 6-year old child.Eur Jpaediatr Dent,2014,15(2 suppl):215-217.
19 Kim YS,Kim GH,Byeon JH,et al.Chromosome 11q13 deletion syndrome.Korean J Paediatr,2016,59(suppl 1):s10-13.
20 Chen RJ,Chen HS,Lin LM,et al.Otodental dysplasia.Ora Surg Oral Med Oral Pathol,1988,66(3):353-358.
21 Liu A,Wu M,Guo H,et al.Clinical pathological and genetic evaluations of Chinese patients with otodental syndrome and multiple complex odontoma:case report.Medicine,2017,96(5):e6014.
22 Cook RA,Cox JR,Jorgenson RJ.Otodental dysplasia:A five year study.Ear Hear,1981,2(2):90-94.
23 Colter JD,Sedano HO.Otodental syndrome:A case report.Pediatr Dent,2005,27(6):482-485.
24 London Medical Database Http://www.Imdatabases.com.
25 Lee ML,Levin LS,Kopstein E.Autosomal recessive sensorineural hearing impairment,dizziness,and hypodontia.Arch Otplaryngol,1978,104(5):292-293.
26 Kantaputra PN,Gorlin RJ.Double dens invaginatus of molarized maxillary central incisors,premolarization of maxillary lateral incisors,multituberculism of mandibular incisors,canines and first premolar,and sensorineural hearing loss.Clin Dysmorphol,1992,1(3):128-136.
27 Aalfs CM,Oosterwijk JC,van Schoeneveld MJ,et al.Cataracts,radiculomegaly,septal heart defects and hearing loss in two unrelated adult female with normal intelligence and similar facial appearance-Confirmation of a syndrome.Clin Dysmorphol,1996,5(2):93-103.
28 Xiao S,Yu C,Chou X,et al.Dentinogenesis imperfecta 1with and without progressive hearing loss is associated with distinct mutations in DSPP.Nat Genet,2001,27(2):201-204.
29 Alsmald O,Meyer BF,Alkuraya F,et al.Syndromic congenital sensorineural deafness,microtia and microdontia resulting from a novel homoallelic mutation in fibroblast growth fator3(FGF3).Eur J Hum Genet,2009,17(1):14-21.
30 Gregory-Evans CY,Moosajee M,Hodges MD,et al.SNPgenome scanning localizes oto-dental syndrome to chromosome11q13 and microdeletions at this locus implicate FGF3 in dental and inner-ear disease and FADD in ocular coloboma.Hum Mol Genet,2007,16(20):2482-2493.
31 Kettunen P,Laurikkala J,Itaranta P,et al.Association of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis.Dev Dyn,2000,219(3):322-332.
32 Charles C,Lazzari V,Tafforeau P,et al.Modulation of Fgf3dosage in mouse and men mirrors evolution of mammalian dentition.Pro Nati Acad Sci,2009,106(52):222364-222368.
33 Olaya-Sanchez D,Sanchez-Guardado LO,Ohta S,et al.Fgf3and fgf16 expression patterns define spatial and temporal domains in the developing chick inner ear.Brain Struct Funct,2016,222(1):131-149.
34 Ziebart T,Draenert FG,Galetzka D,et al.The original family revisited after 37 years:odontoma-dysphagia syndrome is most likely caused by a microduplication of chromosome 11q13.3,including FGF3 and FGF4 genes.Clin Oral Investig,2013,17(1):123-130.
35 Grillo L,Greco D,Pettinato R,et al.Increased FGF3 and FGF4 gene dosage is a risk factor for craniosynostosis.Gene,2014,534(2):435-439.
2 Denes J,Csiba A.An unusual case of hereditary developmental anomalies of cuspids and molars.Fogorv Sz,1969,62(7):208-212.
3 Toledo OA de,Bausells HI,Vono RM,et al.Multiple dental anomaly in three brothers,Case report.Rev Fac Farm Odontol Araraquara,1971,5:207-214.
4 Levin LS,Jorgenson RJ.Familial otodentodysplasia:a“new”syndrome.Am J Hum Genet,1972,24:61A.
5 Levin LS,Jorgenson RJ,Cook RA.Otodental dysplasia:a‘new’ectodermal dysplasia.Clin Genet,1975,8(2):136-144.
6 Witkop CJ Jr,Gundlach KK,Streed WJ,et al.Globodontia in the otodental syndrome.Ora Surg Oral Med Oral Pathol,1976,41(4):472-483.
7 Bloch-Zupan A.The portal for rare diseases and prphan drugs.“Ophanet:Otodental Syndrome.2014 MAR Http://www.orpha.net/consor/cgi-bin/OC_Exo.php?lng=en&Expert=2791
8 Winter GB.The association of ocular defects with the otodontal syndrome.J Int Assoc Dent Child,1983,14(2):83-87.
9 Vieira H,Gregory-Evans K,Lim N,et al.First genomic localization of oculo-oto-dental syndrome with linkage to chromosome 20q13.1.Invest Ophthalmol Vis Sci,2002,43(8):2540-2545.
10 Santos-Pinto L,Oviedo MP,Santos-Pinto A,et al.Otodental syndrome:three familial case reports.Pediatr Dent,1998,20(3):208-211.
11 Sedano HO,Moreira LC,de Souza RA,et al.Otodental syndrome:a case report and genetic considerations.Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2001,92(3):312-317.
12 Stewart DJ,Kinirons MJ.Globodontia.Ararely reported dental anormaly.Br Dent J,1982,152(8):287-288.
13 Enright S,Humphrys AK,Rea G,et al.Globodontia in the otodental syndrome:A Rare Defect of Tooth Morphology Occurring with Hearing Loss in An Eight-Year-Old.Dent Update,2015,42(10):927-930,932.
14 Gundlach KK,Witkop CJ Jr.Globodontia-a new familial tooth abnormality.Dtsch Zahnarztl,1977,32(2):194-196.
15 Mesaros AJ Jr,Basden JW.Otodental syndrome.Gen Dent,1996,44(5):427-429.
16 Beck-Mannagetta J,Muller H,Richter E,et al.Odontomas and pan-tonal hearing loss in the otodental syndrome.Dtsch Zahnazil Z,1984,39(3):232-241.
17 Van Doome L,Wackens G,De Maeseneer M,et al.Otodental syndrome:A Case report.Int J Oral Maxillofac Surg,1998,27(2):121-124.
18 Cehreli SB,Brannon RB,Musselman RJ,et al.Otodental syndrome:a case presentation in a 6-year old child.Eur Jpaediatr Dent,2014,15(2 suppl):215-217.
19 Kim YS,Kim GH,Byeon JH,et al.Chromosome 11q13 deletion syndrome.Korean J Paediatr,2016,59(suppl 1):s10-13.
20 Chen RJ,Chen HS,Lin LM,et al.Otodental dysplasia.Ora Surg Oral Med Oral Pathol,1988,66(3):353-358.
21 Liu A,Wu M,Guo H,et al.Clinical pathological and genetic evaluations of Chinese patients with otodental syndrome and multiple complex odontoma:case report.Medicine,2017,96(5):e6014.
22 Cook RA,Cox JR,Jorgenson RJ.Otodental dysplasia:A five year study.Ear Hear,1981,2(2):90-94.
23 Colter JD,Sedano HO.Otodental syndrome:A case report.Pediatr Dent,2005,27(6):482-485.
24 London Medical Database Http://www.Imdatabases.com.
25 Lee ML,Levin LS,Kopstein E.Autosomal recessive sensorineural hearing impairment,dizziness,and hypodontia.Arch Otplaryngol,1978,104(5):292-293.
26 Kantaputra PN,Gorlin RJ.Double dens invaginatus of molarized maxillary central incisors,premolarization of maxillary lateral incisors,multituberculism of mandibular incisors,canines and first premolar,and sensorineural hearing loss.Clin Dysmorphol,1992,1(3):128-136.
27 Aalfs CM,Oosterwijk JC,van Schoeneveld MJ,et al.Cataracts,radiculomegaly,septal heart defects and hearing loss in two unrelated adult female with normal intelligence and similar facial appearance-Confirmation of a syndrome.Clin Dysmorphol,1996,5(2):93-103.
28 Xiao S,Yu C,Chou X,et al.Dentinogenesis imperfecta 1with and without progressive hearing loss is associated with distinct mutations in DSPP.Nat Genet,2001,27(2):201-204.
29 Alsmald O,Meyer BF,Alkuraya F,et al.Syndromic congenital sensorineural deafness,microtia and microdontia resulting from a novel homoallelic mutation in fibroblast growth fator3(FGF3).Eur J Hum Genet,2009,17(1):14-21.
30 Gregory-Evans CY,Moosajee M,Hodges MD,et al.SNPgenome scanning localizes oto-dental syndrome to chromosome11q13 and microdeletions at this locus implicate FGF3 in dental and inner-ear disease and FADD in ocular coloboma.Hum Mol Genet,2007,16(20):2482-2493.
31 Kettunen P,Laurikkala J,Itaranta P,et al.Association of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis.Dev Dyn,2000,219(3):322-332.
32 Charles C,Lazzari V,Tafforeau P,et al.Modulation of Fgf3dosage in mouse and men mirrors evolution of mammalian dentition.Pro Nati Acad Sci,2009,106(52):222364-222368.
33 Olaya-Sanchez D,Sanchez-Guardado LO,Ohta S,et al.Fgf3and fgf16 expression patterns define spatial and temporal domains in the developing chick inner ear.Brain Struct Funct,2016,222(1):131-149.
34 Ziebart T,Draenert FG,Galetzka D,et al.The original family revisited after 37 years:odontoma-dysphagia syndrome is most likely caused by a microduplication of chromosome 11q13.3,including FGF3 and FGF4 genes.Clin Oral Investig,2013,17(1):123-130.
35 Grillo L,Greco D,Pettinato R,et al.Increased FGF3 and FGF4 gene dosage is a risk factor for craniosynostosis.Gene,2014,534(2):435-439.