基牙牙周组织对不同种类烤瓷牙底冠的反应性初探
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摘要
目的探讨基牙牙周组织对不同种类烤瓷牙底冠的反应性。方法选取2016年5月～2018年5月期间在我院就诊的200例下颌磨牙单冠修复患者,根据底冠所使用的修复材料将患者分为第一组(66例)、第二组(67例)以及第三组(67例)。对三组患者修复前以及修复后1、3个月的基牙龈沟液中Th17型细胞因子(IL-17、IL-21)含量进行检测。结果第一组患者的IL-17及IL-21水平在1个月及3个月的修复后均有了明显的提高,差异有统计学意义(P <0.05);第二组患者在修复后的1个月及3个月龈沟液中IL-17水平显著高于修复前,差异有统计学意义(P <0.05),IL-21水平差异无统计学意义(P> 0.05);第三组患者的IL-17及IL-21水平在1个月及3个月的修复后无明显的变化,差异无统计学意义(P> 0.05)。在修复后的第1、3个月,第一组患者的IL-17和IL-21水平显著高于金合金组和二氧化锆第二组和第三组,差异有统计学意义(P <0.05);第二组的IL-17水平明显高于第三组,差异有统计学意义(P <0.05)。结论相较于第一组患者使用的钴铬合金,第二、第三组患者所使用的金合金、二氧化锆对于基牙牙周组织具有较小的刺激性,修复后龈沟液中的IL-17和IL-21水平较为稳定。
Objective To explore deeplythe reactivity of abutment periodontal tissue to different kinds of base crown of baked porcelain teeth. Methods 200 patients with single crown of mandibular molarswho were treated in our hospital from May 2016 to May 2018 were selected. Patients were divided into the first group(66 cases), the second group(67 cases) and the third group(67 cases) according to the repair materials used in the base crown. The contents of Th17 cytokines(IL-17 and IL-21) in the abutment gingival crevicular fluid of the three groups before repair, 1 month after repair and 3 months after repair were detected. Results IL-17 and IL-21 levels of patients in the first group were significantly improved after 1 month and 3 months of repair, and the difference was statistically significant(P < 0.05).The level of IL-17 in gingival crevicular fluid in the second group was significantly higher at 1 month and 3 months after repair than that before repair, and the difference was statistically significant(P < 0.05).There was no significant difference in IL-21 level(P > 0.05). The levels of IL-17 and IL-21 in the third group showed no significant change after 1 month and3 months of repair, and the difference was not statistically significant(P > 0.05).At the first and third months after repair, theIL-17 and IL-21 levels of the patients in the first group were significantly higher than those in the second group(gold alloy) and the third group(zirconium dioxide), with statistically significant differences(P < 0.05).IL-17 level in the second group was significantly higher than that in the third group, and the difference was statistically significant(P < 0.05). Conclusion Compared with the cobalt-chromium alloy used in patients in the first group, the gold alloy and zirconium dioxide used in the second and third groups of patients have less irritation to abutment periodontal tissue. IL-17 and IL-21 levels in the gingival crevicular fluid arerelatively stable after repair.
Objective To explore deeplythe reactivity of abutment periodontal tissue to different kinds of base crown of baked porcelain teeth. Methods 200 patients with single crown of mandibular molarswho were treated in our hospital from May 2016 to May 2018 were selected. Patients were divided into the first group(66 cases), the second group(67 cases) and the third group(67 cases) according to the repair materials used in the base crown. The contents of Th17 cytokines(IL-17 and IL-21) in the abutment gingival crevicular fluid of the three groups before repair, 1 month after repair and 3 months after repair were detected. Results IL-17 and IL-21 levels of patients in the first group were significantly improved after 1 month and 3 months of repair, and the difference was statistically significant(P < 0.05).The level of IL-17 in gingival crevicular fluid in the second group was significantly higher at 1 month and 3 months after repair than that before repair, and the difference was statistically significant(P < 0.05).There was no significant difference in IL-21 level(P > 0.05). The levels of IL-17 and IL-21 in the third group showed no significant change after 1 month and3 months of repair, and the difference was not statistically significant(P > 0.05).At the first and third months after repair, theIL-17 and IL-21 levels of the patients in the first group were significantly higher than those in the second group(gold alloy) and the third group(zirconium dioxide), with statistically significant differences(P < 0.05).IL-17 level in the second group was significantly higher than that in the third group, and the difference was statistically significant(P < 0.05). Conclusion Compared with the cobalt-chromium alloy used in patients in the first group, the gold alloy and zirconium dioxide used in the second and third groups of patients have less irritation to abutment periodontal tissue. IL-17 and IL-21 levels in the gingival crevicular fluid arerelatively stable after repair.
引文
[1]曹园,唐旭炎.非贵金属材料钴铬合金烤瓷联冠及烤瓷桥修复后基牙咬合力与牙周组织的变化[J].中国组织工程研究, 2017, 21(18):2834-2838.
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[3]田瑞,任佳妮.二氧化锆烤瓷牙与钴铬合金烤瓷牙在牙齿修复上的效果分析[J].养生保健指南, 2016(29):203.
[4]袁媛,邹强.全瓷牙修复过程中颈缘位置设定对牙周组织保护的临床研究[J].中国校医, 2017, 31(5):361-362.
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[7]徐丽辉,王一博,刘芳.玻璃纤维增强型复合树脂桩核修复基牙折断烤瓷牙的临床效果研究[J].航空航天医学杂志, 2016, 27(8):984-985.
[8]吉祖琴.钴铬合金烤瓷牙和二氧化锆烤瓷牙效果对比[J].中外医疗, 2017, 36(27):73-75.
[9]赵靓.边缘嵴技术在临床修复各种牙齿畸形中的应用效果[J].中国现代医药杂志, 2016, 18(8):65-67.
[10]徐启蒙.探讨烤瓷牙夹板对老年牙周病患者修复的效果[J].中外医学研究, 2016, 14(31):128-129.
[11]席俊智,梅朝霞.牙体缺损采用金属烤瓷牙修复的效果观察[J].养生保健指南, 2016(51):193.
[12]王圣娣,彭泽昇,熊莉.烤瓷牙周夹板固定对老年前牙扇形移位患者的治疗效果分析[J].山西医药杂志,2017, 46(7):800-802.
[13]公黎明,李军.不同种类的金属内冠烤瓷牙对形成龈缘黑线影响分析[J].全科口腔医学电子杂志, 2016, 3(10):81-82.
[14]陈晨.氧化锆全瓷修复体应用于后牙种植患者的临床效果分析[J].临床研究, 2017, 25(3):119-120.
[15]周国平,赵永兴,王涛.双侧后牙游离缺失实施栓体栓道式精密附着体义齿修复的效果评价[J].海南医学, 2016, 27(4):653-655.
[2]熊世龙,吴菊兰.二氧化锆烤瓷牙与钴铬合金烤瓷牙在牙齿修复上的效果分析[J].中国医药科学, 2017, 7(4):183-185.
[3]田瑞,任佳妮.二氧化锆烤瓷牙与钴铬合金烤瓷牙在牙齿修复上的效果分析[J].养生保健指南, 2016(29):203.
[4]袁媛,邹强.全瓷牙修复过程中颈缘位置设定对牙周组织保护的临床研究[J].中国校医, 2017, 31(5):361-362.
[5]蒋霞.不同临时冠制作方法对烤瓷牙的效果评估[J].华夏医学, 2016, 29(4):97-99.
[6]方絮,靳赢,高科北,等.烤瓷牙修复对龈沟液内IL-23表达水平的影响[J].上海口腔医学, 2016, 25(1):58-62.
[7]徐丽辉,王一博,刘芳.玻璃纤维增强型复合树脂桩核修复基牙折断烤瓷牙的临床效果研究[J].航空航天医学杂志, 2016, 27(8):984-985.
[8]吉祖琴.钴铬合金烤瓷牙和二氧化锆烤瓷牙效果对比[J].中外医疗, 2017, 36(27):73-75.
[9]赵靓.边缘嵴技术在临床修复各种牙齿畸形中的应用效果[J].中国现代医药杂志, 2016, 18(8):65-67.
[10]徐启蒙.探讨烤瓷牙夹板对老年牙周病患者修复的效果[J].中外医学研究, 2016, 14(31):128-129.
[11]席俊智,梅朝霞.牙体缺损采用金属烤瓷牙修复的效果观察[J].养生保健指南, 2016(51):193.
[12]王圣娣,彭泽昇,熊莉.烤瓷牙周夹板固定对老年前牙扇形移位患者的治疗效果分析[J].山西医药杂志,2017, 46(7):800-802.
[13]公黎明,李军.不同种类的金属内冠烤瓷牙对形成龈缘黑线影响分析[J].全科口腔医学电子杂志, 2016, 3(10):81-82.
[14]陈晨.氧化锆全瓷修复体应用于后牙种植患者的临床效果分析[J].临床研究, 2017, 25(3):119-120.
[15]周国平,赵永兴,王涛.双侧后牙游离缺失实施栓体栓道式精密附着体义齿修复的效果评价[J].海南医学, 2016, 27(4):653-655.